Anyone had quad test without nuchal test?

[PixieCake]

Hi all,

I was too late to have a nuchal test and had a quad test at 15 weeks.

My result was screen negative, 1 in 4,000.

I thought this was good, until my friend told me hers was 1 in 37,000.

I don't wish to be insensitive to those who have tested screen positive, and I know 1 in 4,000 is a low risk, but I am worried that if I had had a nuchal test as well, and it was a bad result, the combined result could mean that my odds are much worse.

I'm 31.

Does anyone know:

a) the average results from a quad test without nuchal test (maybe it is not possible to get an extremely low eg 1 in 37000 without the nuchal test?)
b) whether a screen negative of 1 in 4000 could be made screen positive by combining it with a poor nuchal reading?

Thank you and if anyone else who had quad but not nuchal wouldn't mind sharing their numbers that would be great.

I really don't mean to be horrible (and I do mean this kindly) but please get a grip. It does not matter in the slightest what result anyone else got does it? And even if your result was 1:37 million you could still be that one couldn't you?
I suspect there is more to this anxiety than meets the eye and you need to be careful that you don't spoil the actual experience of your pregnancy worring about things that are never going to happen.

The blood test alone is around 60-70% in detecting a problem.

Have no idea about how it would combine with a poor nuchal reading but like reikizen says - I doubt there is anything to worry about. NHS cut off for high risk varies from 1 in 150-1 in 250 so you are well out of the tricky odds.

I really don't think it's helpful that they tell you actual fiqures soley from a blood test and just should say neg or pos. It just worries people for no reason.

Reikizen,

The reason I am asking about other people's results is that I am trying to work out whether it is possible to get one of the extremely low risk scores from the quad test alone, or whether this is only possible from combining the quad with the nuchal.

I don't need to get a grip thank you, I am merely trying to answer a question about how the tests are calculated since I have not been able to find this online.

There are some extremely well informed posters who use mumsnet and I find it an invaluable source of information.

Yes, it is possible to get scores like 1 in 100,000 from the quad test. The calculation they do to give risk takes into account the false positive/negative rates associated with it. 1 in 4,000 is a very low risk. I'm not entirely sure the quad test is ever combined with the nuchal - I think it's a sightly different set of markers, but I could be wrong.

Thanks SunnyMonday, that's helpful. I'm going to make sure I quiz the doc/sonographer about soft markers at my next scan.

Pixie, I know you are worried but honestly I don't think you need to be thinking about soft markers at your next scan. Anything major will show up, most NHS scans don't routinely look for soft markers unless there is a reason to and in your case, it doesn't seem there is.

Lots of babies have soft markers and it means nothing - it will cause you loads more worry if they go rooting around for stuff for no reason. IME they probably won't look for them without any reason anyway.

Your odds of having a child with one of the major genetic issues is i in 4000. That is huge odds.

Some women on here have tiny odds and would love to your odds. Of course anyone can be the 1 as it were but honestly you are getting worked up for nothing IMHO.

Try and enjoy your pregnancy.