High risk of downs - not sure what to do next

[Cookiemonster13]

Hi all,

I had my scan on Wednesday (13 +4) and all looked fine. Nuchal measurement 2. Got a phone call yesterday saying result from combined screening test puts me at a high risk of Down's syndrome (1 in 51). Looking at results Pappa seems fine 1.07 so can only imagine it's the HCG that is causing concern and my age 41.

I know there is a do nothing option but I need to make a choice as I think it would change the outcome for me. I can have the NIPT or amniocentesis. I can't decide what to do I guess the risk is less than 2% but that doesn't mean it won't happen. The NIPT obviously less invasive but I keep thinking what if I'm in the 1% inaccuracy. Leaning towards amniocentesis so I get an answer but what if I harm the baby. Anyway has anyone been through this. I also can't have amnio for another 2+ weeks so would need to ask for a referral.

Hospital just confirmed that my HCG was very high 4.2

Personally...
I would NIPT asap (privately if necessary) then go from there.

There was a thread on here a few years back about a woman who did amnio, then was in the unlucky 0.5% or whatever and did miscarry as a result and then her test came back negative - really heart breaking stuff.

Good luck 💐

From my personal experience, do the amnio.

I would do the amnio - it’s the only way to have a definitive answer. Risk is miniscule

As above poster, from personal experience I would do the amnio. I've had x3 of them done before.

Why not do the NIPT first and if it comes in as low risk, then do nothing?

The NIPT has a high accuracy rate and is a simple blood draw from you. I've had it done after them spotting several markers associated with Down's Syndrome and the NIPT showed high risk of T21, which was accurate.

I had a 1 in 24 chance last year and took the nipt as the amnio terrified me! I have a completely healthy one year old boy :)