Hello, after ivf I am currently in a living nightmare of having received the highest possible risk score on the combined test for T21 (greater than 1 in 2), despite my embryo being PGT-A tested and coming back normal. NT was normal but HcG was off the scale high and papp-a was low. I had convinced myself that this was just the screening false positive and was age related (just turned 40 when eggs were collected) as I could find no examples of this on any forum, however many times I searched.
However, last Friday I was devastated to learn that the nipt came back as high chance too. Today, at nearly 15 weeks, I will have cvs but seems like that is just confirmatory as it’s now something like 90-95% likely that the baby has it. I just can’t get my head around how this could be happening - I know pgta is not 100% but it’s something like 98% accurate. All I keep finding is posts where people are using pgta to avoid exactly this and others which say how rare it is for nipt to contradict a pgta test. A long shot, but has anyone had this happen to them? Also wanted to post this for balance for people considering pgta in future.