Harmony test after low risk combined

[morganablue]

Hi guys, can I pick your Brain on harmony test? I had it done privately at 10 weeks and results came back inconclusive (which they told me can happen with twins and with ivf pregnancy). I have since done the nhs combined and risk came back as very low (1 in more than 8000 for trisomy 21 and 1 in more than 20,000 for the other two trisomy). I have been offered to do the harmony again or to have a refund (or nearly the whole sum). I am now Nearly 14 weeks.

Would u bother? Have u done the harmony or just the combined?
I am quite indecisive as the whole point. For me was to do it early on.

I had both for both pregnancies. I was 38 old the first time, 42 now. I got high risk from the combined test, and nipt gave me low risk, both times.

I would have had the harmony even if given the low risk at the combined test, as it still misses about 15% of the DS cases, and the majority of the cases that are missed happen to young mums (older mums have higher chances to get a high risk at the combined test, bc of age and the results not being so good, even when there is no DS, and bc they get high risk at the combined they are refereed for more tests like the nipt/harmony one and more DS cases are caught).

it’s your choice in the end, you can also wait till the 20 week scan and see if there are any markers then. Some DS have no markers either, but it’s more likely there will be some.

Personally I would have it. Someone will be the 1 in 8000.