Weird results from combined screening tests (high risk)

[MLC93]

Hi all,

I’ve been looking through thread after thread to see if anyone is in a similar situation to me but I can’t find anything!

I had a combined screening test this week and got the dreaded call to tell me that my pregnancy was a high risk for trisomy 21 & 13.

The weird thing about these results is that the midwife was unable to tell me which part of the test caused this result as everything separately looked fine:

Age: 27 (no concern)
NT measurement: 3.3mm (slightly higher than average but still considered within normal range)
HCG & PAPP-A: both within normal range

With the test returning a high risk result I opted to have the NIPT which I took yesterday and now waiting anxiously for results.

Has anyone else been in this situation? What the hell is going on? I’m worried sick!

My risk was not technically high but 1 in 166 and the cut off is 1 in150. My NT measurement was 3.2 so I think it was that as it is close to the cut off at 3.5.

Hi, these screening tests are strange. I think it's probably the nuchal measurement which is slightly higher (even though its within normal range). Hopefully the NIPT result will reassure you that all is fine.

Hiya, I was just wk seeing what the outcome was on this as I’m in the same situation anxiously waiting for my results to come back as got a 1 in 18 chance of T21? Any help will be much appreciated x

Hi Cherie, my NIPT came back extremely low risk of all 3 that are tested. I am now 35 weeks and all scans seem to show normal growth and nothing of concern! It turns out the combined test can be very misleading and other factors such as BMI are taken into account (I didn’t know this) but they basically throw some numbers into a computer and it throws some results back. The NIPT is a much more accurate test as it tests baby’s DNA. I wish you the very best of luck with your results x