Test results

[Hotpinkangel19]

My test results for Diwns came back as 1-1,500. I'm not sure how to feel. I'm 33, with 3 children and the results have always been in the 1000's with them. Why is it so different?

I'm confused.. do you mean your result came back at 1 in 1500?

Yes, 1-1,500 for Downs.

It's still in the 1000's

I know, maybe I didn't explain properly, it's just lower than any of the results I've had for my other 3 children.

The chances are still remote. But that's all it is, a chance. My friend had a 1:10,000 result and her DD was born with DS. If you want to know for definite you need further tests.

Thank you. And for taking the time to reply.

I was 37 when I had my 3rd and although I can't remember the numbers, they definitely decreased with each pregnancy.

I wouldn't worry too much OP, that's still a very small chance and if you are really worried then you can have further tests. You can always ask your midwife next time you see her why your risk is higher.

Have the NIPT test

I had a 1:14 for DS with one of my twins and an increased NT of 6.1mm. My other twins risk was 1:28000 and NT of 1.3mm. They are 6 months old now and neither have DS or anything else. It's not diagnostic. High risk does not mean baby will have a syndrome and low risk does not mean baby will not have a syndrome. Lots of things can affect the screening and maternal age plays a big part too, which is a factor which pushed my risk up. I was 35 xx

This is why I chose not to have screening with my 2nd child. My results with my first baby came back as "high risk" and caused months of worry. I realised then that I would continue the pregnancy so why have screening? If you need to know for sure you need more tests. 1 in a million and you could still be that 1.

You are probably having a girl ;) they tent to show higher risk score than boys more often.
I had this exact issue with my 3rd, had a risk score around 1:1500 at age of 36, it was a very precise number. With ds at 32 it was something amazing like 1:100000 and with dd at 30 it was I think 1:40000.
Dd was born healthy. I would advice to havr harmony test for piece of mind, the thought of dd having ds never left me until after she was born. It is a very good score in actuality but because other scores were so different it is a worry I totally understand that.

@babynelly2010 Thank you. It is because of the results being so different that I worried. X

Increasing maternal age affects calculation, so increases risk as you get older each time

"But there is one key risk factor for Down syndrome: maternal age. A 25-year-old woman has a 1 in 1,200 chance of having a baby with Down syndrome; by 35, the risk has increased to 1 in 350; by age 40, to 1 in 100; and by 49, it's 1 in 10, according to the National Down Syndrome Society."

www.parents.com/health/down-syndrome/down-syndrome-risks/

I was in a similar situation where my T21 risk with my first baby was 1 in 15000 or something like that, and with my second it was 1 in 1922 mostly due to low Papp-a levels. Neither have Down syndrome. I wish our NHS trust would just tell us "high" or "low" instead of giving the odds!

I'm pretty sure if they ran the blood samples through again the following day it would come up as a totally different ratio but still in the same category of low risk. And that's what matters.

@babynelly2010 We are having a girl :-) you were right!

Congrats!