Is a screening for Down's syndrome ...

[KeepOnPloddingOn]

Generally correct? I know occasionally there can be blips and false positives ... But generally is a high result a positive? I have a 1:27 chance of dc having downs. I have read conflicting info, but some say that getting such a high result generally suggests ds is inevitable - as the screenings are not 100% and a very high result should be taken as a highly likely.

I know this may sound confusing sorry, I am no expert on all this- I have been researching lots and as there are no answers as to why some Get such high results if baby doesn't have downs. So I am starting to believe it means in most cases a very high result such as mine is a 'more than likely' ...

For me it was my bloods giving me this high positive. The nt was 2.10- normal. I am mid twenties.

A result of 1:150 or less is considered high risk by the way. I think if I had a 1:100 it would be different - but our screening was relatively very high ...
Aibu to believe that thiS 1:27 Is not a diagnostic, but a pretty cert dc will have downs....? Any feedback would be appreciated.

I would wait and see with the cvs. They are offering you that because you're higher risk, and then you'll know for sure.

good luck with the cvs.

I am really cynical about the nuchal test btw and didn't have it with either of my pregnancies. There is a false positive rate as high as 1 in 20 That's translates to lot of pregnant women (15k!? assuming 50% have the test and 600k babies born) scared shiteless each year for absolutely no reason.

Hopefully they will soon bring in harmony and put a stop to the madness.

A girl at work had 1:6. Her son didn't have Downs, or any other chromosome disorder.

Another colleague had better odds but still high risk, I forget the actual number but it was certainly less than 1:50. He didn't have Downs either.

Neither couple decided to have the amnio.

Just wanted to wish you all the best anyway, whatever you decide and however things turn out.

Here's some info on the link with bleeding and high screening results www.ncbi.nlm.nih.gov/m/pubmed/17286311/

I'm currently googling for you, trying to find something a bit more helpful x

Wow. Thanks so much Abi! Very interesting read indeed. I s google more along these lines. Thanks so much for your help x

My friend was 1:11. Her DS didn't have downs. I agree with tobysmum that these tests can cause unnecessary heartache. My DD had an unusual heart condition in her 20 week scan picked up by an unexperienced sonographer. This was apparently highly indicative of Downs as told to us by an arrogant consultant before sending us off to GOSH where we were told all was normal.

Keepon I remember your prev thread, just wanted to say good luck with whatever test/s you have. I had 3 amino's and everything turned out fine with the tests, and my babies. Was a very stressful time, so appreciate what you're going through.
Can't add anymore info, as other lovely MN-etters have given plenty of helpful links, but I hope everything works out OK.

I had a 1-330 result and my baby had downs.

It's not that the test causes innecssary heartache, I believe after my experiences that we agree to these test without really understanding the impact of the results.

I do hope the time until you get the result passes quickly. As the others have said, it is just a risk factor based on a number of factors. I had a 1 in 260 chance with my 4th who does not have Downs Syndrome, my SIL had a 1 in 20, she had CVS and my neice does not have DS. My friend had a 1 in 750 chance and her child does have DS. Thinking of you x

Going out soon. Determined to have a good day with my dd and dh :)
Mads- those links were particularly interesting! Maybe it's just a wee girl then! Causing grief already hehe.

Best friend had 1 in 6 with her son and he doesn't have Down's.

I find any kind of statistic confusing tbh.

I didn't have screening with my two late pregnancies but my risk of any trisomy was 1:33 due to my age with DC5.

So that would put me in the high catagory without any screening at all.

DC5 doesn't have DS or any other genetic condition (that we know of).

The only way to get an answer is a diagnostic test.
I hope you have a good day and I am sorry you are feeling stressed during this pregnancy

Hi again, think I may have mentioned this in your earlier post, but no IME the test is not generally accurate - we had a false negative, and I know others in the same boat with false positives.

The only way to know for certain is by having additional chromosome testing.

When my DD was eventually diagnosed post birth I struggled to understand how our ante-natal results could have been so wrong (we had less than 1:1000 change or 0.1%), the best description I got was from our DD's consultant who simply said "it doesn't matter what the odds are, if you are the 1 then you are the 1". From memory they cited the triple test as only being c.2/3 accurate, and is only meant as an initial indicator, hence the additional tests.

Please try not to worry & good luck with your tests. x

This is the one of the reasons I choose not to have the blood test. Your always going to be one in something.

For me and DP we talked about tests because our baby may have another genetic condition, but we also refused a amino even though our medical team were pushing for it.

For us, we didn't mind what the outcome was, he is our son and we will deal with whatever life throws at us and love him.

1:27 means you have 26:27 of your baby not having downs, you should be offered further tests that will look.at babies genes and tell you if baby has downs.

Please stop worrying, hope everything works.out.

My sisters bloodtest showed a 1 in 10 chance her dd would have down syndrome. She didn't have further tests as she wouldnt abort.

Her dd turned out not two have down syndrome, she is however severely Autistic and non verbal - some things just can't be planned for.

Have you considered having the Harmony test? I'm not sure how it compares to having an amnio/CVS as a next step.

Probability is just that, it doesn't give you a yes or no answer.

My friend's sister had a 1:1500 result. Her son has Downs Syndrome. She was that 1 - someone has to be.

I wish you the best, come what may.

I had a long chat with two consultants when I was pregnant. They said there's been much research into parents coping with downs after birth and it seems parents who didn't get a prenatal diagnosis coped much better emotionally with a down birthday which I would have thought the opposite. My last consultant was very blunt that unless I was 100% sure I would end the pregnancy then I shouldn't have the test.

I wish they would ban that test.. I've seen far to many mums to be stressed out over it.

purple my GP has the same view point.

He said ask yourself, would the result of any test lead you to terminate? If the answer is no, don't do it.