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Antenatal/postnatal depression

Sertraline v Duloxetine

11 replies

SoapySnowflake · 14/12/2021 13:18

What tablets have less side effects please? I have been recommended both (not together I might add - on separate occasions!) but I’m very hesitant to start as I’m not usually one to take tablets (I birthed both my children on paracetamol, one induced and one back to back so not easy labours!)

I’ve had 7 months of pure misery and I’m just not enjoying life anymore. I’ve been trying to beat this in my own but I’m getting overwhelmed by my emotions every day and have frequent panic attacks. My husband has had enough.

I’m under the care of a perinatal mental health team so I am receiving help but I’m just so nervous about these tablets!!!

Can anyone reassure me please?

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PanicBuyingSprouts · 24/12/2021 14:03

I've taken Sertraline for 6 months twice. What is it that particularly concerns you? Maybe I can help?

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Dizzywizz · 24/12/2021 14:11

I came off sertraline as it completely stopped my sex drive. Duloxetine also works for nerve pain - I have ms and get nerve pain, plus depression and anxiety. Ok so duloxetine works for the d&a but not enough for pain so changed onto amitriptyline. That has been hell. Pure hell. Trying to come off it but it makes me seriously volition. Locking myself in bathroom crying with poor kids outside. I ran out off it once and it was the worst week of my life. I am amazed I am alive. I have a note not to be given it again (when I finally come off it, been about a year trying) as I am reactive to it apparently.
Plus you can’t drink on it, well I have one or two, any more than that and I go crazy. Ruined a hen do being sick and then crying/wailing for hours.
Don’t go on it.

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Dizzywizz · 24/12/2021 14:12

Amitriptyline is working for me so far

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RandomMess · 24/12/2021 16:16

Duloxetine is hell to come off even miss one dose I got bad withdrawal effects took me 2 years to get off it and it didn't even help my depression 😭

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Palavah · 24/12/2021 16:21

I don't know anything about sertraline but duloxetine is indeed horrible to come off because of the half-life. You can't taper in the same way as you can with fluoxetine, for example.

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knitknack · 24/12/2021 16:23

Duloxetine changed my life - I can’t sing its praises highly enough! (GAD and fybromyalgia, 80mg)

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EmergencyPoncho · 24/12/2021 16:25

I'm on Duloxetine, I am really not sure it's working for me but... I'll try to come off it this year. I've had no negative side effects but you do not want to miss one as a pp has said!

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RandomMess · 24/12/2021 16:26

I had drug scales in the end.

If you have a pain condition then yep worth going on knowing you will be on it for life and probably at a low dose.

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BobbieT1999 · 26/12/2021 00:45

I take duloxetine. It's been amazing, only side effect I've noticed is that I've become less tolerant of heat. Although the benefits outweigh this.

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BobbieT1999 · 26/12/2021 00:47

I've also missed a few doses on occasions and haven't noticed any terrible withdrawal symptoms.

One time I missed several days because of supply issues, my mood definitely dropped but picked up again quickly when I resumed them.

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Haggisfish3 · 26/12/2021 01:03

I’m on duloxetine-changed my anxious life wonderfully and no noticeable side effects for me.

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