stuffit
Thalidomide - drugs are never tested in pregnant women, so the use of thalidomide to treat morning sickness was a huge error of judgement and not based on evidence from clinical trials.
Vioxx is a potent arthritis drug, and the CV side-effects that prompted it's withdrawal were only seen at high doses with long-term use. Actually, the manufacturers withdrew it voluntarily. This was not the decision of any governing body.
I'm not familiar with the acne drugs you mention.
Clinical trials and post-marketing experience are of course limited to the length of time since the drug has been in circulation. They are also based on mass data, and cannot rule out events in individuals. However, this is true of ALL drugs and procedures that are available.
Everyone having surgery is warned of the possible adverse effects of the anaesthetic alone, not including the risks associated with the surgery itself, and those of the follow-up drugs and painkillers. But if you are faced with a life-threatening illness, you will weight up the risks of being treated or not being treated.
All medical knowledge has limits. That will always be the case. There are plenty of things out there, such as aspirin I believe, not to mention all the homeopathic remedies, etc etc that never underwent formal testing before being widely used. Yet this vaccine has been tested in a huge trial and used very widely since. The risks of cervical cancer are well established, so to me it makes sense to take up something that has a good chance of protecting against it.
My personal opinion is that, unless you are anti-vaccination globally (i.e. no MMR, no flu, nothing), then there is no reason based on the data available to be concerned about this vaccine in particular.