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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

To wonder if there will be any fall out from skinny jabs?

558 replies

TheLemonGuide · 20/04/2026 16:40

Everyone I know is now suddenly very slim. Okay, im exaggerating slightly, but genuinely, most of my friends who were previously overweight are all now slim thanks to skinny jabs. I am delighted for them! It seems unbelievable to think that a jab can cure this obesity crisis, but I am so pleased my friends and a couple of family members are able to live a healthier life thanks to this.

My only slight concern is, is this something that is going to be too good to be true? Do you think there will be any long term repercussions, or are we right to just celebrate this medication as a cure for something that so many have been battling for so long?

OP posts:
Beeswacks · 20/04/2026 19:15

HoppityBun · 20/04/2026 19:13

They only help for psoriatic diseases where the person is obese and they’re not being prescribed for psoriatic diseases otherwise. There’s very limited research for this.

It is helping people though, limited research is still research, and will lead to more.

DelphiniumBlue · 20/04/2026 19:16

I wonder about this. My GP won’t prescribe them for me ( overweight and type 2, ) I know its probably cost, but I don’t believe that medics signing off online prescriptions when they don’t know your history and never actually meet you are any different from the dodgy doctors who used to sell slimming tablets( aka amphetamines) ) in Harley Street back in the 80s. The similarity being they’ll sell to whoever can pay for it.
I do know plenty of people who get WLI, who mention casually that it makes them sick, and of course no one really knows what the long term effects are. If they are monitored by one of the online medics, they’re probably not telling them about the side effects in case they withdraw the drugs, and I suspect any monitoring is purely based on what the punter tells them.
It may well be worth it for some one who has a lot of weight to lose and can’t manage it any other way, but the risks are not really known.

WhatNextImScared · 20/04/2026 19:19

gamerchick · 20/04/2026 16:59

Well a lot of people at work have been on them a while and packets of rennies have started to show up on desks. So I'm wondering who's going to be the first to get booked in for gallbladder removal.

Not that I'd say that out loud. It's an interesting private experiment.

This is a risk for anyone losing weight fast for any reason though - not just on the jabs, but through regular methods

mantez · 20/04/2026 19:20

I don't need to use them, but I agree in general that a lot of the questioning about them can come from a place of envy. Envy that obese and overweight people will now be just like those who work out every day, run for miles, and watch their calories, don't drink, avoid cakes and biscuits, and all the obese person now has to do is inject every day.

In fairness, a person who is a stone overweight won't get them (now anyway) and must diy their weight loss and more than likely will feel pissed off about it. Whereas the obese person can get their weight down to below that of the above person and keep it there with maintenance dosage without too much effort.

I think the feeling amongst non users is something like "huh, I have to watch what I eat and drink, so it should be HARD for obese people to do the same since they are greedy and should suffer. But look at them - a few injections and they are slim as a pin. Not fair."

BTW that's not me talking, I am delighted to see people improving their overall health by getting BMI to healthy levels, it saves a lot of medical management for conditions brought on by obesity, and should be a no brainer for any doctor to prescribe really.

It's the performative ingestion by people who don't really need it is the issue now I think.

Is that right or wrong?

AuntChippy · 20/04/2026 19:20

Goldbar31 · 20/04/2026 19:06

You do realise that doesn’t make it ethical.

The mean 92%+ failure rate of drugs in clinical trials is abysmal. These are the facts: drugs progress into clinical trials largely on the basis of animal tests in 2 species, which suggest efficacy and safety. More than 9 out of 10 fail in human testing, and most of this failure is due to toxicity and poor efficacy.

It’s abuse.

The failure rate does not mean it’s abuse and is doesn’t prove wrongdoing. It merely demonstrates how hard biological reactions are to predict.

We’d all love a world without animal testing, but we’re not there yet scientifically. It remains an essential safety step in the development of drugs.

Goldbar31 · 20/04/2026 19:29

AuntChippy · 20/04/2026 19:20

The failure rate does not mean it’s abuse and is doesn’t prove wrongdoing. It merely demonstrates how hard biological reactions are to predict.

We’d all love a world without animal testing, but we’re not there yet scientifically. It remains an essential safety step in the development of drugs.

Please educate yourself on what goes on at facilities such as MBR; monkeys force fed; beagles used because of their temperament to inhale poison and bleed out.
Then let me know whether you still think it’s not abuse.

Frugalgal · 20/04/2026 19:31

MyLimeGuide · 20/04/2026 19:09

Its a real concern!! Lots of evidence given and many cases on severe side effects. And this is only beginning. Only a matter of time before it becomes illegal and THEN we really will have a problem!! Obesity x100000 because no one is learning how to be healthy, they are cancelliing it out with drugs, makes no logical sense IMO

I hope this is a joke!!

Frugalgal · 20/04/2026 19:33

JengaCupboard · 20/04/2026 16:52

I agree - I don't think 'faux concern' aka jealous of my skinny friends comes in to it.

You're injecting yourself with no training or real medical supervision. Vague online questionnaires with no proof of answers actually required. Getting cheaper by the day.

Don't get me wrong, a literal cure for being overweight sounds great, and something I would definitely consider, but I do wonder whether the rush to market/increasing options/minimal supervision etc will eventually come back and bite us.

There's no vague questionnaire. I am on Mounjaro and I periodically have to send them a video with proof of my identity and the date and wearing tight clothes so they can see the shape of my body!

10namechangeslater · 20/04/2026 19:34

SilenceInside · 20/04/2026 17:04

Oh fgs. YABU to start a "concern" thread about weight loss injections.

@TheLemonGuide the decision making process by those with access to the evidence, the MHRA in the UK, is that the benefits for people who are obese/overweight with a weight related health condition outweigh the possible risks. What part of that decision making process do you think is wrong, flawed or somehow misguided?

Anyone can start a thread about anything they like including weight loss injections.

Frugalgal · 20/04/2026 19:34

TheLemonGuide · 20/04/2026 16:47

I am slightly overweight myself, and would consider taking it (if I’m allowed to, as I’m not sure if you need to have a certain bmi to start). That’s part of the reason I’m curious.

You generally need to have a BMI over 30.

bumptybum · 20/04/2026 19:35

hahabahbag · 20/04/2026 16:56

I’m actually really worried that there will be long term repercussions which in a country with socialised medicine means potentially a cost to us all not to mention additional pressure on our medical services. I’m overweight but will not take a medication which my dr hasn’t prescribed and no proper oversight

From what I understand the prescribers notify your GP

NeverDropYourMooncup · 20/04/2026 19:36

HoppityBun · 20/04/2026 19:13

They only help for psoriatic diseases where the person is obese and they’re not being prescribed for psoriatic diseases otherwise. There’s very limited research for this.

My Rheumatologist says that she's seen multiple people with inflammation and disease activity levels plummeting almost as soon as they've started using them and before they've lost any significant weight. She's hoping that further research can look into the effects upon the inflammatory response so they could potentially prescribe them even at lower doses than needed for weightloss.

ButterYellowHair · 20/04/2026 19:38

They’re GLP1 obesity medication. Not skinny jabs.

Mummyoflittledragon · 20/04/2026 19:42

Placestogo · 20/04/2026 18:00

And death… you forgot to mention death…. We are all going to die!!!

I don’t think it’s a laughing matter to ridicule the risk of developing eating disorders. My dd has anorexia and it is a mental illness and certain people-do have a genetic predisposition to it. Although anorexia can be inherited, we don’t know if we have this until starting the cycle of weight loss. The red carpet is starting to fill up with seriously underweight women. Sharon Stone realised how gaunt she had become. Some celebs do not look well at all. That could be mentally as well as physically. pagesix.com/2026/03/15/celebrity-news/stylists-fear-stars-are-blind-to-how-skinny-they-really-are/

moderate · 20/04/2026 19:43

Goldbar31 · 20/04/2026 19:29

Please educate yourself on what goes on at facilities such as MBR; monkeys force fed; beagles used because of their temperament to inhale poison and bleed out.
Then let me know whether you still think it’s not abuse.

Any lifestyle outside of Jain fruitarianism involves abuse of other living things. Please educate yourself about how the phrase “please educate yourself” is always counter-productive outside of little virtue-signalling circles.

10namechangeslater · 20/04/2026 19:43

I’m very sceptical about them. I have a BMI of 31 at the moment but I won’t be using them anytime soon. I find there is a lot of defensiveness from those that are using them.

Goldbar31 · 20/04/2026 19:49

moderate · 20/04/2026 19:43

Any lifestyle outside of Jain fruitarianism involves abuse of other living things. Please educate yourself about how the phrase “please educate yourself” is always counter-productive outside of little virtue-signalling circles.

Really poor justification for abuse.

Binus · 20/04/2026 19:50

I've always had the impression at least some of the worries people voice about WLIs are genuine and well meant, but that doesn't stop them from being one sided. Such people would be taken more seriously if they made sure to be clear they understand that not taking WLIs is more likely than not to mean a person is still obese in the long term, and that this also comes with side effects.

wldpwr · 20/04/2026 19:50

We definitely know of some down sides already. I've lost 4 stone on Mounjaro but I've developed gallbladder disease and the surgeon has forbidden me from taking it anymore. He said he seen an increase in gallbladder disease in GLP 1 users. (He also told me to lose weight for the surgery... go figure!)

moderate · 20/04/2026 19:52

Goldbar31 · 20/04/2026 19:49

Really poor justification for abuse.

Do you eat meat? Drink milk? Decapitate cauliflowers that are just trying to live out their natural lives?

You think the place you’ve drawn the line is ethically defensible, when you know full well that others choose more defensible lines than you?

InfoSecInTheCity · 20/04/2026 19:54

wldpwr · 20/04/2026 19:50

We definitely know of some down sides already. I've lost 4 stone on Mounjaro but I've developed gallbladder disease and the surgeon has forbidden me from taking it anymore. He said he seen an increase in gallbladder disease in GLP 1 users. (He also told me to lose weight for the surgery... go figure!)

I developed gallstones and ended up hospitalised with a severe infection resulting in emergency surgery. This was after losing 4 stones a few years ago with just willpower, calorie counting, exercise and feeling starving all the time. Weight loss in general is a trigger for gallstones, as ironically is weight gain.

NoSoupForU · 20/04/2026 19:57

No faux concern here. I want all of my loved ones to be happy and healthy.

I've seen a number of them use injections and all but 1 have put the weight back on when they stopped using them. The one who hasn't has done tremendously well on them and completely changed her entire approach to food and fitness. 2 of my friends have suffered quite severe issues after using them.

I think if it works it works. My only concern is people using them without any sort of monitoring like blood tests etc.

wldpwr · 20/04/2026 19:59

InfoSecInTheCity · 20/04/2026 19:54

I developed gallstones and ended up hospitalised with a severe infection resulting in emergency surgery. This was after losing 4 stones a few years ago with just willpower, calorie counting, exercise and feeling starving all the time. Weight loss in general is a trigger for gallstones, as ironically is weight gain.

This is absolutely true but it's also a listed side effect of GLP-1s.

Usernamechanging · 20/04/2026 20:01

hahabahbag · 20/04/2026 16:56

I’m actually really worried that there will be long term repercussions which in a country with socialised medicine means potentially a cost to us all not to mention additional pressure on our medical services. I’m overweight but will not take a medication which my dr hasn’t prescribed and no proper oversight

You know that the online pharmacies inform your GP? My GP phoned me to ask me to go in for a once over about 5 months in. Happy I've finally lost some of my weight. No concerns.

InfoSecInTheCity · 20/04/2026 20:02

punkhairbrush · 20/04/2026 18:18

Why are people on weight loss drugs so defensive when anyone has questions or concerns about the drugs? So much anger towards the OP for no reason.

For me the biggest concern is how it it totally skewing the body image debate for women yet again! I saw an advert today saying ‘want to lose weight?’ And showing an average size woman, who probably wouldn’t even be allowed to get the drug! I feel very much we’re back in the height of ‘nothing tastes as good as skinny feels’ era! It’s really sad. Wanting to lose weight because you’re obese is one thing. Not feeling worthy if you’re above a size 8 is another thing! Very dangerous messaging!

Nope. Sorry but just no.

fat people are blamed for encouraging poor health through the positive body image movement, now formerly fat people are blamed for encouraging poor health an overly skinny body image. It is absolutely fucking impossible to win here. Too fat and you’re awful for society, get to a healthy weight and you’re awful for society.