Yes.
I was the subject of workplace bullying in two previous positions. In the one I am in now, I was targeted and put on a totally unfair and unjustified PIP.
I fought back and got the union involved and raised an unrelated grievance about unfair treatment of me.
I can almost guarantee they'll leave this 'underdog' alone now.
My Dad, xmas 2021, threatening me after dinner, wealthy, middle class 70 year old bloke squaring up to me like a bloody thug. This time however, I didn't move, kept my composure and asked him repeatedly to please get out of my way, please let me pass etc. I can swear he did a cartoon-like head shake before he moved (and I left, not returning for our usual drinks/games gathering that evening).
My ex, similarly, tried it with me when we were still living together but seperated. I looked her in the eye and told her that I was not scared of her any more and she'd have to find someone else to bully now.
Silence. Our paths still cross (she still lives in my house that she rents from me and we share a dog). Nobody is nicer to me than her, now!
Sometimes a 'fuck this' is required, despite any societial 'rules'.