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Human embryos made from human skin cells

145 replies

HeyThereDelila · 30/09/2025 23:10

AIBU to think we’re sleep walking in to dystopia?

Scientists in the US have created the first embryos using human skin and sperm, raising concerns that babies could be born who ultimately don’t have a genetic female parent.

While this technology looks to be a decade away from being viable, here our fertility regulator (HFEA) met to discuss it in January 2025: they think it’ll be here soon.

Reproductive technology seems to be heading to a very concerning place, with all the emphasis on people who want children, come what may, and none of the emphasis on children’s rights or needs.

https://www.bbc.co.uk/news/articles/c4g2vyee0zlo

A clear petri dish stands is illuminated from below through an aperture in a black platform. There are blobs of fluid in the petri dish and two needle-like implements are there to perform microscopic manipulation of embryos

Human skin DNA fertilised to make embryo for first time

US scientists testing the technique say it could help people overcome infertility and potentially allow same-sex couples to have a genetically related child.

https://www.bbc.co.uk/news/articles/c4g2vyee0zlo

OP posts:
Allthatshines1992 · 01/10/2025 11:33

GreenFairy93 · 01/10/2025 11:00

Wow. Just wow.

Taking a child from a third world country, to be raised in another country with no link to the lor culture, heritage or the language they speak to be raised by white saviours is SO MUCH MORE DAMAGING than being donor conceived.

I'm honestly gob smacked you think it is better to take children half way round the world to a place they will never feel they belong to be raised in an alien culture with no links to what they knew as a young child is somehow superior.

Have you ever seen documentaries about orphanages around the world? This was one about orphans in Ukraine:

There are lots of countries like this.

- YouTube

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https://youtu.be/Cs42-5HnQRQ?si=7jfwYCM7oaZUzNzh

Finteq · 01/10/2025 11:37

InTheMountainsThere · 01/10/2025 05:32

An unlimited number of embryos being created to be experimented on would obviously be the biggest ethical concern, followed by pushes to normalise surrogacy (both emotionally blackmailing women into "altruistic" surrogacy for relatives/ family friends, and paid surrogacy advocates claiming "reproductive work is work" and trying to claim paid pregnancy and birthing is the same as working in tescos and an option unemployed women should be instructed to consider, as well as the normalising of exploiting women in low income countries to an ever increasing extent...). It's common knowledge that surrogate pregnancy is much higher risk to both mother and baby than pregnancy with the woman's own eggs.

There's also the danger mentioned in the article of babies with recessive genetic syndromes being created from only one set of genetic material, and the designer baby being "returned" because the individual paid for a healthy baby and doesn't want their disabled one.

The one advantage for women is an end to women being paid for egg donation and the dangers of ovarian hyper stimulation syndrome (also a risk in IVF to create her own pregnancy) etc.

Imagine if they just birthed female children- which weren't considered humans.

To be used as incubators so they could continue their experiments and the offer up surrogacy/ babies for the highest price.

persephonia · 01/10/2025 11:43

Allthatshines1992 · 01/10/2025 11:33

Have you ever seen documentaries about orphanages around the world? This was one about orphans in Ukraine:

There are lots of countries like this.

A lot of the children in the orphanages aren't orphans though. In some cases they have family members who visit them but can't care for them because of poverty or the child's needs. It's a legacy from the institutionalisation of disabled children/orphaned children/children from broken homes in Soviet times. Reforming the systems mean supporting children to live at home with their families instead, or moving them to smaller, family like foster homes... and changing attitudes. There may well be children there who would benefit from adoption, but they often have complex needs and need for more proactive help than most children to thrive.
Charities like LUMOS are actively involved in this area.

InTheMountainsThere · 01/10/2025 11:45

Finteq · 01/10/2025 11:37

Imagine if they just birthed female children- which weren't considered humans.

To be used as incubators so they could continue their experiments and the offer up surrogacy/ babies for the highest price.

Selecting embryos for sex before transferring them has been possible in IVF for decades. It's even been routine for decades, where both parents carry the gene for a disorder that only effects one sex. So that wouldn't happen by accident.

The ethical problems of surrogacy, paid egg donation (or any egg donation not done as part of a mother's own fertility treatment) and of embryos created purely to experiment on are far more immediate and real than any chance of women being irradicated.

GreenFairy93 · 01/10/2025 11:47

Allthatshines1992 · 01/10/2025 11:33

Have you ever seen documentaries about orphanages around the world? This was one about orphans in Ukraine:

There are lots of countries like this.

This is awful and must be tackled by Ukraine. The solution to this is not international child trafficking.

I assume you are pressuring fertile people to bring foreign orphans into the country and use them to build their family and be white saviours to these poor children too? Instead of having their own children obviously, because this is morally superior.

No child should be born instead of saving an orphan because orphans need parents and wanting your own child is irrelevant according to you. How can anyone actually make a baby when they should be saving the worlds orphans!? Right!? Or is it just the infertile couples who should shoulder the weight of the world's orphansge crisis alone? It usually is in the eyes of people like you.

FirstCuppa · 01/10/2025 11:48

persephonia · 01/10/2025 11:03

There are ethical issues with donor eggs too. It's a much more invasive process than sperm donation and can have consequences for the donors. But what is involved in this would mean:

  • the egg cell from one anonymous woman is stripped of all its genetic material
  • the genetic material from someone else is artificially placed inside it and then half of that chucked
  • The egg is then fertilised with more genetic material
  • the egg is then placed in the body of another (unimportant) woman until birth
  • the resulting baby is then taken away from the (unimportant) birth mother after birth and given to the commissioning parents to raise. Presumably the two people who contributed the genetic material. Who may be male/female or male/male or less likely female/female.

It's really hard to work out who "actually" is the parent in that scenario. It's incredibly complicated, in a way it could never be in nature, and just feels incredibly unethical. All so two people can be the "genetic parents". There's a certain arrogance about genetic legacy there I can't put into words.

Exactly - like a ready made meal full of hyrid bits of animals packaged up in something that seems edible but actually has no nutrition because it's been engineered out. UPF turns into UPBabies.
Imagine forming 9 of these with defects and STILL CONTINUING

unconditionalpurelove · 01/10/2025 11:51

YANBU, selfish selfish people.

FirstCuppa · 01/10/2025 12:00

Also -science is figuring out epigenetics with huge advancements in treatment and care incoming. Why are we fucking about with what we have spent so long and billions trying to find answers to?

I honestly can only think it's about creating a race of "children" that won't be considered the same, be it as organ donor or army fodder, they won't be able to get treated using the same techniques. Maybe Trump thinks super race right now. Idiotic and dangerous man.

Northquit · 01/10/2025 12:07

Will they have jars in the Central London Hatchery and Conditioning Centre?

Allthatshines1992 · 01/10/2025 12:07

GreenFairy93 · 01/10/2025 11:47

This is awful and must be tackled by Ukraine. The solution to this is not international child trafficking.

I assume you are pressuring fertile people to bring foreign orphans into the country and use them to build their family and be white saviours to these poor children too? Instead of having their own children obviously, because this is morally superior.

No child should be born instead of saving an orphan because orphans need parents and wanting your own child is irrelevant according to you. How can anyone actually make a baby when they should be saving the worlds orphans!? Right!? Or is it just the infertile couples who should shoulder the weight of the world's orphansge crisis alone? It usually is in the eyes of people like you.

A lot has been extrapolated in that comment. That's not what I'm saying at all. I love people who adopt. It's a wonderful thing to do if you are able to do it.

The children in documentaries like this one have more pressing concerns than their culture and heritage, like not being raped by other children in the institutions, finding warmth in a cold tiled room, hoping the staff will feed them something, hoping for some sort of medical care. Avoiding violence from other children in these institutions.

Allthatshines1992 · 01/10/2025 12:09

Notmymarmosets · 01/10/2025 10:28

They absolutely will be able to gestate a baby in a simulated womb soon. No question. That will be a huge money spinner.

It has already been done with a sheep

Finteq · 01/10/2025 12:12

InTheMountainsThere · 01/10/2025 11:45

Selecting embryos for sex before transferring them has been possible in IVF for decades. It's even been routine for decades, where both parents carry the gene for a disorder that only effects one sex. So that wouldn't happen by accident.

The ethical problems of surrogacy, paid egg donation (or any egg donation not done as part of a mother's own fertility treatment) and of embryos created purely to experiment on are far more immediate and real than any chance of women being irradicated.

They're experimenting on embryos

The point I was trying to make is- at what point do these embryos have rights?

At the moment they are just making embryos.
Then they will try to grow them and continue to experiment on them- apparently the above embryos had genetic defects.

At what point will the embryos be considered to have rights that prevent them being treated so inhumane and not just as property.

FirstCuppa · 01/10/2025 12:14

Finteq · 01/10/2025 12:12

They're experimenting on embryos

The point I was trying to make is- at what point do these embryos have rights?

At the moment they are just making embryos.
Then they will try to grow them and continue to experiment on them- apparently the above embryos had genetic defects.

At what point will the embryos be considered to have rights that prevent them being treated so inhumane and not just as property.

Edited

Another Q is are they human just because they have mixed human DNA? Are we still classing that as human when it is made by a manufactured process rather than biologically viable? IVF was effectively mimicry, whatever this is, it ain't that.

Finteq · 01/10/2025 12:17

FirstCuppa · 01/10/2025 12:14

Another Q is are they human just because they have mixed human DNA? Are we still classing that as human when it is made by a manufactured process rather than biologically viable? IVF was effectively mimicry, whatever this is, it ain't that.

If they are fully grown- they will be human, regardless.of any genetic defects- or if their intelligence is impaired because of the genetic defects.

Finteq · 01/10/2025 12:19

The problem.comes if they don't have any parents- or if the cells used are over 100 years old.or something- so the baby doesn't have an advocate- instead just a business intent on exploitation.

InTheMountainsThere · 01/10/2025 12:22

Northquit · 01/10/2025 12:07

Will they have jars in the Central London Hatchery and Conditioning Centre?

I know it's not the point, but when I think of Brave New World the first thing that pops into my head is that Huxley got foetal alcohol syndrome quite wrong ...

olderandnonthewiser · 01/10/2025 12:25

Made me think of Frankenstein

Allthatshines1992 · 01/10/2025 12:51

Finteq · 01/10/2025 12:19

The problem.comes if they don't have any parents- or if the cells used are over 100 years old.or something- so the baby doesn't have an advocate- instead just a business intent on exploitation.

Human embryos can be frozen for up to 50 years in the UK right now. They slowly deteriorate and I'm not sure they could actually produce a viable offspring after 100 years.

FeralWoman · 01/10/2025 13:24

@Finteq If embryos have rights then women lose their rights. The USA is an example of this. There should be a list of responsibilities and safeguards surrounding the embryos but they can’t be given rights because that would sacrifice living breathing women’s rights.

persephonia · 01/10/2025 14:54

FeralWoman · 01/10/2025 13:24

@Finteq If embryos have rights then women lose their rights. The USA is an example of this. There should be a list of responsibilities and safeguards surrounding the embryos but they can’t be given rights because that would sacrifice living breathing women’s rights.

Not only is it bad for women, it also creates weird legal limbos for the embryos themselves which are potentially unethical.

persephonia · 01/10/2025 14:59

Allthatshines1992 · 01/10/2025 12:51

Human embryos can be frozen for up to 50 years in the UK right now. They slowly deteriorate and I'm not sure they could actually produce a viable offspring after 100 years.

That's embryos. If this method was actually developed you wouldn't necessarily need the skin cells etc to be "fresh" so long as they were preserved well enough for the DNA to be intact. So a child could be born where it's genetic parents (whatever that means in this context) were long dead. Even if they weren't, I don't think someone who had donated eg skin cells for use in this way would automatically feel the same protectiveness that a parent would. They would be even further removed from the process than a sperm donor or egg donor today is.

ExpertInAbsolutelyZero · 01/10/2025 15:09

It is unethical and dehumanising, making future generations commodities to be bought and sold on a whim.

LadyoftheMercians · 01/10/2025 15:13

Reproductive technology seems to be heading to a very concerning place, with all the emphasis on people who want children, come what may, and none of the emphasis on children’s rights or needs.

We already have this?

We have parents who are shit and neglect their dc.

We have ivf so inherited illnesses which would stop reproduction are ignored.

LadyoftheMercians · 01/10/2025 15:16

Allthatshines1992 · 01/10/2025 10:21

Anyone who wants to adopt should. It's honourable and they deserve to be commended for it

What, even the paedophiles?
(Deliberately being goady just for the comment)

boberto88 · 01/10/2025 15:24

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