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Share your dilemmas and get honest opinions from other Mumsnetters.

Human embryos made from human skin cells

145 replies

HeyThereDelila · 30/09/2025 23:10

AIBU to think we’re sleep walking in to dystopia?

Scientists in the US have created the first embryos using human skin and sperm, raising concerns that babies could be born who ultimately don’t have a genetic female parent.

While this technology looks to be a decade away from being viable, here our fertility regulator (HFEA) met to discuss it in January 2025: they think it’ll be here soon.

Reproductive technology seems to be heading to a very concerning place, with all the emphasis on people who want children, come what may, and none of the emphasis on children’s rights or needs.

https://www.bbc.co.uk/news/articles/c4g2vyee0zlo

A clear petri dish stands is illuminated from below through an aperture in a black platform. There are blobs of fluid in the petri dish and two needle-like implements are there to perform microscopic manipulation of embryos

Human skin DNA fertilised to make embryo for first time

US scientists testing the technique say it could help people overcome infertility and potentially allow same-sex couples to have a genetically related child.

https://www.bbc.co.uk/news/articles/c4g2vyee0zlo

OP posts:
Hols23 · 01/10/2025 08:19

Iguessicoulddothat · 01/10/2025 07:00

Still need an egg with no genetic material to put the DNA from skin in, cant get rid of us pesky women that easily!

Don't like the age angle. But it's fascinating science and no child would ever be a "freak"

Yes - still need an egg to carry the genetic material, and still need a woman to carry the baby. It's chilling that women in these situations would be reduced to carriers of babies entirely created by men. How can that possibly be ethical? Just because we can, doesn't mean we should.

BeMellowAquaSquid · 01/10/2025 08:21

Maybe I would feel differently if I didn’t have healthy children myself but part of me thinks this is going too far and humans are meddling with things they just shouldn’t meddle with.

FirstCuppa · 01/10/2025 08:30

Hols23 · 01/10/2025 08:19

Yes - still need an egg to carry the genetic material, and still need a woman to carry the baby. It's chilling that women in these situations would be reduced to carriers of babies entirely created by men. How can that possibly be ethical? Just because we can, doesn't mean we should.

The ethics are so worrying precisely because it is by men for men in my opinion. Putin would likely make an army, Xi might make an army of organ donors or for science experiments. Will they be treated as children or cattle?

Considering so many women are choosing not to have children and the West is having a drop in birthrate it isn't hard to conclude that this meant to help women, just uses them.

IsletsOfLangerhans · 01/10/2025 08:42

aurynne · 01/10/2025 06:36

I have worked with the technique and generated animal embryos myself with it, which went to develop into healthy adults, many times, so I can assure you I am well aware that babies conceived this way would be completely indistinguishable from babies conceived "naturally".

We used to have a facility where we invited members of the public to come to see the cloned animals. They invariably left disappointed. They were completely normal cows and goats living their normal cow and goat lives. They didn't glow in the dark, have two heads or talked back to them.

But by the words you write, you have already convinced yourself of the opposite, so it's a bit useless for me to explain this, even from my point of view as a user of that specific technology you're talking about. I just hope that, when this technology becomes mainstream just like IVF already is now (and you are utterly unable to tell which babies are IVF and which are not unless you're told), you won't be one of the weirdoes holding banners asking for these children to be hanged in the town's main square.

It isn’t just SCNT, it is a new technique which removes half the chromosomes artificially to create a haploid cell (they’ve called it mitomeiosis). As someone else who has worked in this field, I can’t see it becoming useful at all in the near future. All sorts of issues with imprinted genes, epigenetic reprogramming etc.

GreenFairy93 · 01/10/2025 09:12

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incognitomouse · 01/10/2025 09:21

My first thought when I read this was WHY.

WHY are scientists wasting time, money, resources on this when we have so many cruel illnesses and diseases we still don't have cures or treatments for?

HeyThereDelila · 01/10/2025 09:29

It’s not about being “uneducated drama llamas”, it’s about seeing the real motive behind this: huge profits and a continuation of attempting to monetise reproduction.

This process isn’t remotely like IVF, nor should we just shrug and move on because it’s apparently similar to cloning and that was done years ago.

It’s treating women’s eggs and uteruses like carrier bags, and for what? For whom? So women in their 50s who don’t have viable eggs can have genetic babies made from their skin cells, or so two men can make a baby.

Do any of you who support this ever stop and put yourself in the shoes of the child who would be one of only a handful in the world growing up without a genetic female parent? We already know many commissioning parents in surrogacy never see/speak to the surrogate mother again.

Try looking at the experiences and testimonies of donor conceived children and adopted adults to see the psychological harm caused.

This is monstrous.

OP posts:
GreenFairy93 · 01/10/2025 09:43

HeyThereDelila · 01/10/2025 09:29

It’s not about being “uneducated drama llamas”, it’s about seeing the real motive behind this: huge profits and a continuation of attempting to monetise reproduction.

This process isn’t remotely like IVF, nor should we just shrug and move on because it’s apparently similar to cloning and that was done years ago.

It’s treating women’s eggs and uteruses like carrier bags, and for what? For whom? So women in their 50s who don’t have viable eggs can have genetic babies made from their skin cells, or so two men can make a baby.

Do any of you who support this ever stop and put yourself in the shoes of the child who would be one of only a handful in the world growing up without a genetic female parent? We already know many commissioning parents in surrogacy never see/speak to the surrogate mother again.

Try looking at the experiences and testimonies of donor conceived children and adopted adults to see the psychological harm caused.

This is monstrous.

Donor conceived children have been studied into adulthood and it has been found that if the child's parents are honest with them about their birth story from the start and it is just part of their story they are not psychologically harmed by being donor conceived.

Some do not want to meet their donors, some don't. Many are very proud of the fact their parents wanted them so much and that they were born intentionally to loving families, not by accident to parents who didn't plan them. They are no one giant conglomerate of emotionally damaged victims. The narrative that they are on MN drives me up the wall. No one I know in real life thinks this. The most important thing for a child is to have two living parents and to grow up in a safe and stable loving home.

KimberleyClark · 01/10/2025 09:46

It’s sad when people want children and can’t have them, but it doesn’t justify this kind of experimentation. I say this as someone unable to have children.

HeyThereDelila · 01/10/2025 09:48

But your point doesn’t take in to account all those who struggle, feel a sense of detachment from families or genealogical bewilderment- plenty of testimonies online to support this @GreenFairy93

We’re increasingly seeing “double donation” where a single woman uses a donor egg and donor sperm, often imported. Genetic father may be Danish, genetic female parent Spanish, birth mother English. This is all being done for the benefit of adults, not the children. And egg donation is done by young working class women for money, risking their health in the process. But who cares as long as wealthy people in their 40s and 50s can buy donor eggs, ey?

OP posts:
GreenFairy93 · 01/10/2025 09:58

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Allthatshines1992 · 01/10/2025 10:05

So they've found a way to take a woman's egg, erase her DNA and replace it with that of a man's. So two men can pay some poor woman in another country to carry their baby and then take it away.

Allthatshines1992 · 01/10/2025 10:08

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NotEnoughKnittingTime · 01/10/2025 10:12

Duckduckagogo · 01/10/2025 06:17

I'm glad I'll be dead before these fucking freaks grow up. And freaks they will be.

You would think have thought my IVF kids were forty years ago.

NotEnoughKnittingTime · 01/10/2025 10:13

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Some of us don't want to adopt. I am guessing you didn't did you?

MrsSkylerWhite · 01/10/2025 10:15

Happytap · 30/09/2025 23:15

I saw this and it made me feel sick. Just because we can doesn't mean we should.

Agree. Reported that all 9 resultant embryos had significant abnormalities. That’s enough to just stop, surely?

Allthatshines1992 · 01/10/2025 10:17

NotEnoughKnittingTime · 01/10/2025 10:13

Some of us don't want to adopt. I am guessing you didn't did you?

What you want is all that matters to you

MrsSkylerWhite · 01/10/2025 10:17

aurynne · 01/10/2025 06:36

I have worked with the technique and generated animal embryos myself with it, which went to develop into healthy adults, many times, so I can assure you I am well aware that babies conceived this way would be completely indistinguishable from babies conceived "naturally".

We used to have a facility where we invited members of the public to come to see the cloned animals. They invariably left disappointed. They were completely normal cows and goats living their normal cow and goat lives. They didn't glow in the dark, have two heads or talked back to them.

But by the words you write, you have already convinced yourself of the opposite, so it's a bit useless for me to explain this, even from my point of view as a user of that specific technology you're talking about. I just hope that, when this technology becomes mainstream just like IVF already is now (and you are utterly unable to tell which babies are IVF and which are not unless you're told), you won't be one of the weirdoes holding banners asking for these children to be hanged in the town's main square.

But why? Why do we need cloned anything at all?

NotEnoughKnittingTime · 01/10/2025 10:18

Allthatshines1992 · 01/10/2025 10:17

What you want is all that matters to you

Don't dodge the question. Why should it be the infertiles who should adopt? Anyway it is very expensive and difficult to adopt so maybe they couldn't do so.

Allthatshines1992 · 01/10/2025 10:20

incognitomouse · 01/10/2025 09:21

My first thought when I read this was WHY.

WHY are scientists wasting time, money, resources on this when we have so many cruel illnesses and diseases we still don't have cures or treatments for?

I'm sure this will create new retardations embedded in a person's genetic code and in turn introduce new diseases to the gene pool.

Allthatshines1992 · 01/10/2025 10:21

NotEnoughKnittingTime · 01/10/2025 10:18

Don't dodge the question. Why should it be the infertiles who should adopt? Anyway it is very expensive and difficult to adopt so maybe they couldn't do so.

Anyone who wants to adopt should. It's honourable and they deserve to be commended for it

MrsSkylerWhite · 01/10/2025 10:24

NotEnoughKnittingTime · 01/10/2025 10:18

Don't dodge the question. Why should it be the infertiles who should adopt? Anyway it is very expensive and difficult to adopt so maybe they couldn't do so.

Anyone who is concerned about the cost of adoption (does it cost if you go through the legal process in the UK? Didn’t think so?) or indeed IVF should probably not be considering raising a child, which is very costly.

HeyThereDelila · 01/10/2025 10:24

@GreenFairy93 payments have stood at £985 since October last year - a significant draw to young working class women in a cost of living crisis. It’s paid directly in to bank accounts in to flat payments - no itemised receipts needed. It’s payment, not “expenses”. By contrast sperm donors get £45 and kidney donors must provide strictly itemised receipts.

Over 4000 women from the 3 poorest social income deciles have “donated” their eggs since 2011- when payments rose to £750. Over 800 women aged just 18-25 have “donated” since 2000. DHSC didn’t do an impact assessment before they increased payments to egg “donors” in October last year, nor have they ever undertaken studies on the long term risks to women’s health of egg retrieval. Fertility clinics don’t track long term health outcomes in donors either.

Do you honestly think it’s ethical to ask an 18 year old to go through egg retrieval so older people can buy their eggs?

I’m sorry for your illness but you didn’t need donor eggs: you wanted them.

OP posts:
Lookeye · 01/10/2025 10:27

I just think it gets proven time and time again that nature knows best. And we should stay well out of it. The law of unintended consequences….

NotEnoughKnittingTime · 01/10/2025 10:27

MrsSkylerWhite · 01/10/2025 10:24

Anyone who is concerned about the cost of adoption (does it cost if you go through the legal process in the UK? Didn’t think so?) or indeed IVF should probably not be considering raising a child, which is very costly.

So children for the wealthy only? Luckily all my embryos came from a NHS round.