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AIBU?

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Genetic mutation in a quarter of all Labradors hard-wires them for obesity

3 replies

Everdecreasingcircumferences · 07/03/2025 07:42

https://www.newsweek.com/labrador-dogs-more-hungry-genetic-mutation-1876630

Genetic drive to overeat evidenced by University of Cambridge scientists and found in labradors and people. Those studying obesity have said for years that it's nature not nurture and it's not as simple as "greed" - this latest discovery backs this up.
For those with these genetics it's not impossible to manage weight but they do have to work much, much harder at it in our food environment. AIBU to think that this proves slimness is no more a moral superiority than being a natural blonde or not needing to wear glasses?

It doesn't mean we don't still have responsibility to work on managing weight and fight obesity, the same way if we have poor eyesight it is up to the individual to use corrective lenses - but it does prove that Weight Loss Injections are no more "cheating" than wearing contact lenses is.

hungry labrador

Some Labradors are "hungry all the time" for a good reason, scientists warn

Research has found that 25 percent of Labradors have a genetic mutation that means they get hungrier than other dogs.

https://www.newsweek.com/labrador-dogs-more-hungry-genetic-mutation-1876630

OP posts:
Catza · 07/03/2025 08:04

You are conflating unrelated issues in your post.
Labradors are not humans. There is a reason why we have human studies following animal/invitro studies. A gene which makes Labradors more hungry (and it isn't a new information - Labrador owners are well aware of this fact and knew it for decades) is pretty irrelevant in terms of contextual validity. Labradors don't have the same agency or capacity for reasoning to make decisions as humans.
Jabs are not cheating mostly because we don't know who is cheated and out of what. It will only be cheating if you are entering a weight loss competition with ToS stipulating "natural weight loss".
But this is in no way related to Labradors or genes.

lostintherainyday · 07/03/2025 08:07

Catza · 07/03/2025 08:04

You are conflating unrelated issues in your post.
Labradors are not humans. There is a reason why we have human studies following animal/invitro studies. A gene which makes Labradors more hungry (and it isn't a new information - Labrador owners are well aware of this fact and knew it for decades) is pretty irrelevant in terms of contextual validity. Labradors don't have the same agency or capacity for reasoning to make decisions as humans.
Jabs are not cheating mostly because we don't know who is cheated and out of what. It will only be cheating if you are entering a weight loss competition with ToS stipulating "natural weight loss".
But this is in no way related to Labradors or genes.

From the article “Interestingly, the POMC gene affected similar brain pathways in humans as it does in dogs. These findings in the Labradors are consistent with previous research into humans with mutations in POMC, who often become obese at a young age.”

Catza · 07/03/2025 08:10

lostintherainyday · 07/03/2025 08:07

From the article “Interestingly, the POMC gene affected similar brain pathways in humans as it does in dogs. These findings in the Labradors are consistent with previous research into humans with mutations in POMC, who often become obese at a young age.”

I don't see how this in any way disproves my post which is about contextual validity and agency that humans (unlike Labradors) have over their decisions. Or how it disproves my point that genetic mutations in Labradors and humans are in no way related to the idea that jabs are/aren't cheating.

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