To consider mounjaro?

[RustyandDusty]

I'm 5 foot 3 and 10 stone 4. I'm a size 10 still but wobbly. I have pcos. I've done work with a personal trainer and at the gym. Diet generally good but I cannot shift a stone. Aibu to use mounjaro for 1 month?

Lots of people report weight loss from week one.

That doesn't answer the question. Medically, why is it safer for someone with a BMI of 29 - who used to be 30 - to take these drugs that someone who is BMI 29 but has never reached 30?

Both are likely to be overeating. BMI is not a precise measure. It's a pretty arbitrary cut off and will be questioned as time goes on (IMO).

Saying "obesity is a chronic condition" is meaningless. "Chronic" just means "Chronic diseases are defined broadly as conditions that last 1 year or more and require ongoing medical attention or limit activities of daily living or both." No one is checking if someone has had a BMI of 30+ for more than a year before prescribing weight loss jabs.

Because safety where drugs are concerned is all about relative risk.

Let’s say that Mounjaro carries a 5% increased risk of cancer (it doesn’t, this is just for illustration purposes).

And let’s say that obesity carries a 20% increased risk of cancer.

Someone who is not obese would be silly to increase their cancer risk by 5%.

Someone who is obese would be sensible to reduce their cancer risk by 15%.

So what are the actual relative risks @HotCrossBunplease, as opposed to the hypotheticals? (Also noting that the use of the blunt instrument of BMI has not been addressed).

An individual's relative risk may be very different to the general population. E.g. someone who has had a hysterectomy has a different set of risks from HRT than someone who still has their womb.

Prescribing guidelines for HRT include questions about hysterectomy etc.

Prescribing guidelines for weight loss drugs include questions that would mean some people who do qualify on BMI grounds can’t be prescribed them.

Beyond that, it’s impossible to cater for all individual circumstances and data analysis has clearly been done which has concluded that the use of a BMI cutoff is reasonable approach, albeit a very broad-brush one.

The side effects are awful op.

4lbs a week at OP's BMI? On 2.5? Not going to happen.

DH hasn't found that. He's three months in. What bad side effects did you suffer from?

Ridiculous. I'm 5 ft 3.
Ive used Wegovy to go from 14 st 3 pds, now 10 st 9 pds. It's taken a year, and I'm now weaning down to try and come off. To want to start it at your weight to lose a few pounds is stupid and disordered.