I guess this is where the 'in sickness and in health' bit comes in, when you marry OP. I know that sounds harsh, but my DH and I have gone through something, possibly worse, bearing in mind that a PP indicated that your DH's symptoms may be possible to control given time. For us, we'd been together 7 years, then got married. Eleven months later, I became disabled. Suddenly I was unable to do so many of the things that we'd always taken for granted, long walks, hill climbs, long flights, etc, but bless him, my DH took it in his stride. I often worried that I was stopping him living his life, but always told him, and still do, that if there's something he wants to do that I can't, then he really must go ahead and do it, even if secretly I would hate him going off and leaving me to do things I no longer can, but that's just selfish on my part, and I am so grateful that he has rarely done this. He tells me that he married me to be with me, and if that means we can't do all the things we once could, well, we'll find other things that we CAN do together. I don't necessarily think you're being selfish, but if you really love your DH, then try and think of him, and how he's feeling. It may also be useful to remind him occasionally, that there is ALWAYS someone out there who is worse off than himself. I feel sure that given time, you will adapt to the new situation, and who knows, if they get the drugs right, it may not even be an issue a few months down the line. However, if you feel that your DH is getting depressed and not doing things that he CAN do, but is wearing the dressing gown of doom, and wallowing in self pity, then do try and get him to talk to his GP about it, as he needs to find a way of adapting to this life change. This also applies to you, as it's not unusual for family members to feel down when they suddenly find their lives have been severely curtailed by the illness of a family member. I hope it all works out for the best, but to some degree, it can be what you and your DH choose to make of it. Good luck!