I have been taking them for about 2 and a half weeks. The day after I started them, my acid reflux went through the roof. ( i have a hiatus hernia/gerd/ibs-c) and heard they would help me so much, people rave about them. I have been having so much gas and my heart has been skipping beats like mad, due to vagus nerve getting irritated. Has anyone else ever experienced this? Horrible!