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AIBU?

Share your dilemmas and get honest opinions from other Mumsnetters.

Low Cortisol Levels

7 replies

strawthatbrokethecamelsback · 15/06/2023 16:15

shamelessly posting for traffic - I've tried Menopause and General Health with no replies

Has anyone got any experience with Low Cortisol Levels?

I had a blood test last week as I'm feeling very down, depressed, massive lack of energy or motivation and absolutely zero sex drive. The Dr I spoke to was lovely & ordered a raft of tests but she specifically wanted a Cortisol Blood test before 9am. Everything else has come back ok but the Cortisol is borderline low at 225. Dr Google says a level of 170 is serious concern but most normal levels are at over 430

I'm trying to pin the Dr's down to going through this and also to follow on from my previous conversation but the earliest I can speak to someone is 30th June! I realise it's not life threatening but I do feel totally rotten. I have 4 year old twins and it's not been an easy ride. I'm 43 and pretty certain I'm peri menopausal as well as maybe a bit depressed. My FSH has come back at 9.9, which is maybe a little high for my age but not drastically so. I also went through 5 rounds of IVF, not sure if that's relevant but I'll put it there anyway.

So to summarise do anyone have any experience with this? If so what treatment did you have and more importantly did it make you feel better?

OP posts:
QOD · 28/06/2023 23:33

No but I’m in the same boat. 9ak cortisol level of 210
’very urgent’ referral by Gp to an endocrinologist but the wait is stupid so using my insurance and going private. Even then, I’ve got to wait until 20 July
hopefully someone will come along with some info

zerored · 29/06/2023 00:05

There are some helpful forums on Facebook about Addison's disease and adrenal insufficiency. Fingers crossed that you just have naturally low levels rather than there being a serious problem. However, if it is adrenal insufficiency it can be life threatening if your cortisol drops too low. You'd be given steroids and have to take extra when feeling unwell/periods of stress etc, which should keep you safe. Sometimes a problem with the pituitary gland can cause low cortisol so the doctor may want to rule that out too with pituitary tests and possibly an MRI. Secondary adrenal insufficiency can also be caused by taking a lot of steroids E.g Inhalers if asthmatic. My understanding is that this is more common than primary adrenal insufficiency (Addison's disease), though I'm far from an expert!

Run4it2 · 29/06/2023 01:09

My son had this, and had extreme tiredness. Ended up being admitted to hospital and adrenal insufficiency tests carried out then. The tests were fine, and they concluded that the low levels were due to poor sleep. Eventually diagnosed with b12 deficiency and vitamin d deficiency.

BonstanceBarroll · 29/06/2023 07:22

Watching with interest, as my husband and son (12) both have low cortisol/adrenal insufficiency. Frustratingly and worryingly, the care/treatment they are both receiving are poles apart.

Son's cortisol results for AM have been as low as ~80, but typically ~120 and he is struggling with school, depressed, exhausted, always run down...yet the endo consultant is of the 'watch and wait' attitiude, and the cons secretary is useless; forgets to send out blood forms, months of inaction, missed details in letters??
Same with his abnormal thyroid, autoimmune markers and low iron stores (which I spotted on lab report - cons missed it?) and abnormal MRI showing a 'partially empty sella' - a slightly squished pituitary gland. She doesn't think it is connected. I promise I am not making this up, I wish I was.

I have had to instruct the cons else nothing happens, push for specific blood tests, short synacthen test, MRI...the original response was to just monitor him and refer to a sleep clinic! Managed to organise a short synacthen test, which showed a normal response, so this cemented the theory that this issue was from the pituitary gland. This has dragged on for 2 years, and still we are fighting t get him treated. We now have a second opinion organised via the same team.

He is also high functioning autistic so life at school has been a battle as it is, and now this. We are on the cusp of complaining, yet again, as he has just been left, forgotten; his symptoms arose in 2019 yet we had to wait almost 2 years to be seen and still, here we are with zero treatment, sending endless emails, calls and a fear that he could collapse with an adrenal crisis. He also has a dangerous heart condition. GP hands tied. We feel as though nothing will change from their POV until he collapses/dies.

Husband - also chronically fatigue and was being told it was stress/lack of sleep etc...I suggested a cortisol screening via GP and these readings showed similar results to our son! Referall to a very proactive consultant who has carried out the short synacthen test (normal) but opted to treat the low cortisol, ordered an emergency steroid injection kit and treat the wonky thyroid. All within a year.

I looked into a private referall for our son despite being very low income, as was so terrified at the lack of care via the NHS yet seeing how my husband has been cared for, I now see that there is a serious failing by this particular endo. All I can say is, don't be fobbed off, do your research via trusted sources (NICE guidelines, endocrinologist organisations, charities that support those with adrenal insufficiency even if you don't have this, as it gives an idea of the pathways taken when there is a clinical suspicion).

Good luck with the investigations. I am not medically qualified. All I would say if I was in your situation is do your research via professional resources and go armed and prepared when you see the doctor/specialist; look into the day long cortisol screening, I believe this is the saliva test or even read up on the short synacthen test plus possible autoimmune screenings, and don't forget the thyroid function.

strawthatbrokethecamelsback · 29/06/2023 13:04

BonstanceBarroll · 29/06/2023 07:22

Watching with interest, as my husband and son (12) both have low cortisol/adrenal insufficiency. Frustratingly and worryingly, the care/treatment they are both receiving are poles apart.

Son's cortisol results for AM have been as low as ~80, but typically ~120 and he is struggling with school, depressed, exhausted, always run down...yet the endo consultant is of the 'watch and wait' attitiude, and the cons secretary is useless; forgets to send out blood forms, months of inaction, missed details in letters??
Same with his abnormal thyroid, autoimmune markers and low iron stores (which I spotted on lab report - cons missed it?) and abnormal MRI showing a 'partially empty sella' - a slightly squished pituitary gland. She doesn't think it is connected. I promise I am not making this up, I wish I was.

I have had to instruct the cons else nothing happens, push for specific blood tests, short synacthen test, MRI...the original response was to just monitor him and refer to a sleep clinic! Managed to organise a short synacthen test, which showed a normal response, so this cemented the theory that this issue was from the pituitary gland. This has dragged on for 2 years, and still we are fighting t get him treated. We now have a second opinion organised via the same team.

He is also high functioning autistic so life at school has been a battle as it is, and now this. We are on the cusp of complaining, yet again, as he has just been left, forgotten; his symptoms arose in 2019 yet we had to wait almost 2 years to be seen and still, here we are with zero treatment, sending endless emails, calls and a fear that he could collapse with an adrenal crisis. He also has a dangerous heart condition. GP hands tied. We feel as though nothing will change from their POV until he collapses/dies.

Husband - also chronically fatigue and was being told it was stress/lack of sleep etc...I suggested a cortisol screening via GP and these readings showed similar results to our son! Referall to a very proactive consultant who has carried out the short synacthen test (normal) but opted to treat the low cortisol, ordered an emergency steroid injection kit and treat the wonky thyroid. All within a year.

I looked into a private referall for our son despite being very low income, as was so terrified at the lack of care via the NHS yet seeing how my husband has been cared for, I now see that there is a serious failing by this particular endo. All I can say is, don't be fobbed off, do your research via trusted sources (NICE guidelines, endocrinologist organisations, charities that support those with adrenal insufficiency even if you don't have this, as it gives an idea of the pathways taken when there is a clinical suspicion).

Good luck with the investigations. I am not medically qualified. All I would say if I was in your situation is do your research via professional resources and go armed and prepared when you see the doctor/specialist; look into the day long cortisol screening, I believe this is the saliva test or even read up on the short synacthen test plus possible autoimmune screenings, and don't forget the thyroid function.

Oh my goodness that sounds hellish, you poor things! Only thing I could suggest is to contact PALS at the hospital to make a complaint or ask for a referral to a different hospital.

coincidentally my daughter see’s an endocrinologist for her short stature, he’s always been brilliant with her, although no treatment given just wait & see. I’ll definitely mention it to him when we see him again in the next couple of months. I moved all of her care to a specialist Childrens teaching hospital as our local hospitals were useless.

I’m due to have a conversation with the GP tomorrow about my results. I emailed them today as I’ve had terrible nausea, which has subsided but now the dizziness and light headedness is really bad. I’m sure it’s all connected.

good luck with your son, honestly I would try and get him referred to another consultant, maybe in a different hospital

OP posts:
BonstanceBarroll · 30/06/2023 08:00

strawthatbrokethecamelsback
Thank you for your kind and considered reply - PALS are on radar AGAIN fortunately.
Very good point regarding moving all care to a large teaching hospital, as our son is currently under 3 trusts for different issues and still no general paed. Looking at GOSH now, thank you.

Good luck with your GP and I hope you get the tests/referrals that you require, as it sounds like you are having a really tough time. Interestingly, my son AND husband also had dizziness, nausea and it transpired that they had occasional hypoglycaemia due to the pituitary gland affecting the pancreas.

Ultimately, son has a type of autoimmune polyendo condition. Both are autistic and have various genetic 'flaws', yet husband has been told that he has autistic burnout and adrenal 'fatigue' by GP but endo says it is a cortisol insufficiency as SST showed that adrenals are fine. Its the pesky pituitary gland with both!

Very best to you and your family X

strawthatbrokethecamelsback · 30/06/2023 11:09

BonstanceBarroll · 30/06/2023 08:00

strawthatbrokethecamelsback
Thank you for your kind and considered reply - PALS are on radar AGAIN fortunately.
Very good point regarding moving all care to a large teaching hospital, as our son is currently under 3 trusts for different issues and still no general paed. Looking at GOSH now, thank you.

Good luck with your GP and I hope you get the tests/referrals that you require, as it sounds like you are having a really tough time. Interestingly, my son AND husband also had dizziness, nausea and it transpired that they had occasional hypoglycaemia due to the pituitary gland affecting the pancreas.

Ultimately, son has a type of autoimmune polyendo condition. Both are autistic and have various genetic 'flaws', yet husband has been told that he has autistic burnout and adrenal 'fatigue' by GP but endo says it is a cortisol insufficiency as SST showed that adrenals are fine. Its the pesky pituitary gland with both!

Very best to you and your family X

Good luck to you too. We’re under Sheffield Childrens hospital and I can honestly say the treatment and general care is above and beyond what our local hospitals provided. You absolutely have the right to change and do whatever is best for your son

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