When my kids were small, I kept a spare duvet cover under the bed in each bedroom. Before I had children, a house 3 doors down lost 2 of their 3 children in a house fire. Parent got into the room but couldn't get the kids out. This haunted me and I decided I could lower a baby or toddler out of a first floor window inside an empty duvet cover. Even if it didn't go right to the ground, it would hugely reduce the distance they would be falling from. I kept one in every child's room until the youngest was 5 or so. Even today we have an agreed escape plan for a fire (and ladders stored on the side of the house for easy access).
Other top tips include using a towel on the pillow for a vomiting child - you just change the towel rather than having to keep changing sheets and pillowcases.
Oh and after a bad dream, you shake the nasty dream off the pillow onto the floor and turn it over to the nice dream on the other side of the pillow. I still do this now I am in my 50s!
For safety or ease, what do you do? Any brilliant ideas?