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Desperate for hope or advice please! (MH-related)

8 replies

PumpkinPieAlibi · 01/02/2021 13:45

Feeling a bit hopeless and would desperately like any reassurance or advice that anyone can give please. Before I say anything else, I am not in the UK, so any comments re: the NHS and accessing help via that method doesn’t apply here, unfortunately.

My DP and I have been together since 2011 and he has always been a calm individual, able to compartmentalize well and not prone to extremes of emotion, but generally positive with hopes and dreams. Around 2014, I noticed that he started getting irritated more often and was just generally more pessimistic. His mood and outlook have progressively become more depressed over time to the point where I would say he had high-functioning /chronic depression aka dysthymia. He just never seemed excited or sad about anything and never wanted to leave the house if he could help it. In Jan 2019, he started getting panic attacks, tried a couple therapy sessions and then continued as normal but clearly something was brewing since then.

2020 was a particularly bad year as his dad died in March (he did not cry or seem sad at all), his brother was sectioned in a mental hospital in October and he was the lead on a big work project that meant he was working Sunday-Sunday and gone from 5 a.m. – 7 p.m. with no overtime pay. It all came to a head in Dec 2020 and he had what I can only call a breakdown. He stopped wanting to do anything – showering (normally showers 2x a day), working out (he works out 6x a week normally), had no appetite, isolated himself, stopped speaking much to anyone and mentioned that he had suicidal thoughts.

I immediately booked an appointment with a psychiatrist and he has been put on 50mg Pristiq (desvenlafaxine) which is an SNRI and Alprazolam. He is experiencing some scary side effects including a tremor that manifests whenever he becomes anxious or tries to drive, headaches, dizziness and insomnia. But the thing is, it’s been 4 weeks and there have been very few changes. He has a little more energy and his mood has probably gone from a 1/10 to a 3/10 but nothing else has really changed. He still wants to be alone, has no motivation for anything and is still experiencing suicidal ideation.

My question – how long do SNRIs take to really have an effect? Has anyone tried desvenlafaxine and did it work for you? Would an increased dosage or a new drug be better?

His doctor would like to monitor for another 4 weeks before considering changing the dose or switching but is hopeful that he will respond. The thing is, my DP isn’t hopeful at all. I know it’s probably the depression talking but he says this is just who he is and he isn’t optimistic that the medication will change. Now he is saying he doesn’t want kids (was ambivalent previously but was willing to have one), he is pushing me and all his family away, he hates the idea of getting up and working everyday having done it for the past 11 years and thinks that life is pointless if he can’t find a better work/life balance (he is up by 4, leaves home by 5 and is home sometimes after 6. He has a very stressful job in network engineering). To complicate things, 2 of his 3 brothers have bene diagnosed with schizophrenia but the doctor is not concerned that he is manifesting any symptoms of same and at his age (34), it is likely he would have already shown signs.

I am just so sad and stressed and hopeless right now. We were supposed to be getting married this year and have a 3-week European honeymoon planned for next year but he doesn’t care at all about any of that. We have (had?) a great relationship and love spending time together but now we barely speak as he wants to be alone, we don’t really hug or laugh or anything.

WHAT NOW? Is too early to be this worried? Is it likely that another medication might help if this one doesn’t? He is supposed to be starting therapy in a month or so and he has a lot of buried issues from childhood but will that really help?

Any thoughts welcome please. I just need something to hold on to.

OP posts:
PumpkinPieAlibi · 01/02/2021 14:42

bump

OP posts:
NRE20 · 01/02/2021 18:44

I have no first-hand experience with this type of depression, nor am I a medical professional, so bear this in mind with my advice, but it sounds as though the GP needs to try something new now, if you’ve not seen a significant change in his mental state in 4 weeks. Can the counselling be moved forward too? Seems worth it, even if it involves paying privately for sessions.
And what about you? This situation has been going on for a long time and is affecting not just your present, but seemingly your future too, if you want to have children and that could well be off the table. Living with someone with MH issues, must be extremely draining and is no doubt affecting your own MH, as you struggle to stay strong for your DP.

Cargill · 01/02/2021 22:56

I'm sorry he is going through this, and it must be so hard for you. Would he be able to have some sick leave from work, or consider looking for a less stressful job ( realize that might be difficult while he is so ill though)- it sounds as if stress has been building up for a while, and he is burnt out and maybe needs a break from it all. His working hours sound horrendous- has his sleep suffered as well? It doesn't sound as if he has time for anything to help him relax and enjoy life outside of work- does he tend to worry about it when he is at home as well? Did he have a health check, including bloods, to rule out any physical issues that may be impacting on his mental health? It might be that he needs to have some changes to his lifestyle to make a recovery, and it may take some time moving in small steps - ultimately I don't believe any job is worth sacrificing your sanity and relationships for. I hope the therapy helps - best wishes to you both

bellropes · 01/02/2021 23:51

It's usual to try an SSRI first. I wonder why he's on an SNRI. I know Venlafaxine (SNRI) can be sedating and people can feel sluggish on it. Alprazolam will cause sedation as well. It can take 6-8 weeks for the full antidepressant effect to kick in. See how it goes then request a med review if there's no real improvement. Ask why he's on an SNRI as well.

CSIblonde · 02/02/2021 01:33

After 4 weeks he should be better than what you're describing. Generally depression meds take 3weeks to kick in. I cant see why the 4 more weeks wait for a higher dose. Have you asked why? From experience, I really don't get why they start on such low doses then are surprised when you are no better. Most people I've met on support forums are on at least 100mg ( Sertraline, Citalooram etc)before starting to feel better I tend to get pushy now & point out that the 50mg rhey always suggest after you've had a break has never touched it before, so it's not going to now: & they seem to accept it .

pumpkinbump · 02/02/2021 01:40

I think he definitely needs a break from work. He sounds exhausted. Can you get a second opinion from another doctor? I am not sure why they have ruled out other issues when it clearly runs in the family.

TaraR2020 · 02/02/2021 18:54

Oh op what a horrible time for both of you Flowers

Severe depression can take longer to respond to anti depressants, 4 weeks is the point at which you may start to feel an affect so it's not unreasonable for his GP to want to give it a bit longer.

It can take time to find an anti depressant that works well for one person, so it's important to give each one a fair try. However, if either of you feel he is getting worse while on them then definitely seek an urgent appointment with his GP.

Don't despair if it does take a few attempts to find an anti depressant that helps, if this situation should occur it may simply mean that the ones tried are not helping enough, not that they don't help at all. Another reason to try a different anti depressant would be if the one he takes helps but he experiences side effects that are problematic. He may find that the tremor he's experiencing may be reason enough to want to explore other medications.

I would hope that, with suicide ideation, his GP is keeping a close eye and providing weekly or even fortnightly check ups to monitor his condition?

There is light at the end of the tunnel and I've known a few people to go through similar or worse and recover, but I think you need to prepare yourself for the fact that recovery may take time and may not happen as quickly as you hope.

Therapy can be brilliant for many people, but again there are many different types of therapy so if he's not getting on with it straight away there are other forms he could try that could prove transformative.

You mention he has issues from childhood to work through, so it's possible that therapy may prove difficult for him to start with.

I agree with pp that time off work could be helpful for him. I also think its imperative you ensure you have a solid network of support around you, because you need it as much as he does.

Don't worry too much at this point about him changing his mind about children etc. He isn't in his right mind atm and when he is unable to take care of himself he can't be expected to consider being responsible for an infant. Dont get upset, just let the topic rest and give him time to recover and regain his hope for the future.

I really hope you are feeling supported by family, friends and your own doctor. Open up to them as much as you feel you can, it's very tough supporting a loved one through a mental health crisis. If his family and friends can help support too, that would be great.

It will get better, Op, and you will both come through this Flowers

DameFanny · 02/02/2021 19:02

Not a medic but 2 things stood out - you say his mood has gone from 1/10 to 3/10 - so that's actually a significant improvement, even if it doesn't feel that way right now. I don't have experience of SNRIs, but if it's not unusual for them to take 4 - 8 weeks for full effect then you're still on target

You also say there's schizophrenia in the family. IIRC there's a genetic link between schizophrenia in one generation and depression and bipolar disorders in subsequent generations. (Studies in the Amish in the 1980s I think)

It might be worth the doctor looking at mono-polar bipolar? Just because that might require longer term medication, and different choices might be made?

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