...To think that antidepressants can stop working?

[BigSoftPillow]

Just wondering if anyone has experience of their antidepressants not being effective and more?
Ds has been taking sertraline for almost 7 months now. It took a month or so before he noticed a difference but they seemed to help and he was back to his old self.
The last few weeks I've noticed he is quiet,shuts himself in his room etc
Ironically he was fine during lockdown!
He has said to me today he is going to see the GP as he feels the AD arnt working anymore. I'm proud that he has recognised this as it was a real struggle to even get him to the GP 8 months ago!
Is this a common thing? Will the GP just up the dose?
He started on 25mg and went to 50mg after 2 weeks.
TIA

they can definitely bottom out. i’ve had 3 med changes in the last 2 years. currently on vortioxetine and mirtazapine for antidepressants and quetiapine anti-psychotic/mood leveller.

i’ve been on prozac, effexor and sertraline before and none of them worked for me. the vortioxetine is a ‘new’ med for long-term treatment resistant depression. along with the mirtazapine it’s been working ok.

i take a fuckton of other stuff as well, i think i’m currently up to 20 different meds.

Blimey @fucknuckle I hope all those drugs help you🌷
I hope doubling up the dose works, I think if DS has to go through this every 6 months he will give up