Posting here for traffic really; but I'm not sure what to do for the best as it is a sunday and cant call my doctor. I have re-started my sertraline, having previously been on 150mg then stopped for 10 weeks. I was on 50mg but increased my dose to 100mg yesterday, after my tablet this morning I have muscle twitching, am sweating quite a bit (mostly on my palms and chest), have quite a fast heart rate (120bpm when I checked), I've not had these side effects before I generally only get the nausea and brain fuzz when I take it. I don't know if I should wait till tomorrow to call my doctor and maybe not take tomorrows dose until I've spoken to them; or try and call out of hours for advice today I've never had side effects begin so quickly after taking a pill before. I know what I'm like and if I google this I am likely to overthink and over react - my partner thinks I overreact to everything - so I'd appreciate some outside opinions on what's best to do.