I know people who do craft stuff and sell it from home, and some who buy and renovate antiques/curios and sell those.
Before children I had a 'proper' full time career working for a large corporation in HR, and was lucky enough to be able to work from home whenever I didn't have team meetings or client meetings - the flip side was I also did a lot of travelling and overnights hence why I stopped when I had a family. But it was the best combination ever - lots of flexibility, treated like an adult/professional, lovely colleagues in a bustling office when I was in there - and a great remuneration package!
When my DCs were small I realised I'd go mad without some sort of outside work (apart from doing my self-employed DHs books....) and took a post as a clerk to the governors in the local secondary school. It's perfect for parents as I do three evening meetings a term and the rest is flexible working from home. I organise meetings, type the minutes, and do a million and one other admin/HR/legal/marketing /comms/recruitment/etc type stuff which keeps the brain alive and gives me the chance to wear office clothes and speak to grown ups occasionally! I learned a huge amount about public sector working (and funding!), education and schools, local community stuff and so on, and it's perfect for parents of school-age DCs. I do around 9 hours a week, mostly in term time only. The downside is that the pay is barely above minimum wage, there's no company car and no bonus scheme.....
But yes - there are jobs out there, I loved my old job and am pretty happy with my current one (done 10 years now). Good luck finding something.