So I am off to read the Lancet paper, which I suspect is more nuanced, but the guardian reports that if from 40 onwards I drank an extra glass of wine a day I would shorten my life by 30 minutes. At face value, that sounds a fantastic deal: five minutes of pleasure a day for about 40 years, ie about 50 days, in exchange for 30 minutes’ less time as I die. Around 2500x pleasure than loss. A great deal, I think.