As for things to do in Orlando. The main area is mostly park based ime:
Disney - 4 theme parks, 2 water parks
Universal - 2 parks, 1 water park
Seaworld - 1 park, 1 water park
About an hour or so drive away:
Kennedy Space Centre
Busch Gardens
various beach resorts, west coast is better imo
There are other things to do, but when we go we focus on Disney and Universal, and of for a fortnight - a trip to the space centre.
Re flights - we prefer to go with Virgin, flying into Orlando. A few friends have done non direct flights and saved money, but i definitely wouldn't recommend that for a week's holiday.
We've been going over the part 13 years and each time we check out the best ways to book. Sometimes it is a package via Virgin, sometimes direct with Disney and other times doing it all separate. We have stayed in hard Rock Hotel, a couple of Disney hotels and private villas. We had a dining plan with Disney last time which was good - came 'free' with our package and it definitely saved us money.
I;d look at all the options.