We have three freezers :) One combo fridge/freezer in the kitchen (Freezer 1), an upright freezer in the garage (freezer 2) and a decent size chest freezer a bit further into the garage (freezer 3). I adore all of them for different reasons!
Freezer 1 has the "ongoing / in use" stuff - open bags of frozen veg, chips, frozen meals in bags and containers, open bag of sausages, beefburgers etc.
Freezer 2 has the "we need this periodically" stuff - loaves of bread (goes mouldy too fast it we leave it in the pantry), unopened bags of veg, frozen cake from previous birthdays (we portion it up and put it in lunchboxes every now and again), butter packs, food waste which is frozen in bags in the bottom drawer and then put into the bins on collection morning. It's well organised (thanks DH) and is easy to get stuff as all in drawers.
Freezer 3 currently has 1.5 pigs in it (in the form of bacon, hams, sausages, mince, chops) and half a cow (in the form of joints, mince and steaks). It's invaluable and means we can have organic home grown meat delivered once every 3-6 months. I also know the butcher who processes the animals so I get to choose exactly what goes into the sausages and I know how they are slaughtered which alleviates somewhat my ethical concerns over eating meat.
I don't find it particularly difficult to rummage around in the chest freezer to pick out what we need from it but then it really only contains meat and so it's very easy to organise. Big joints in the central part, cardboard box of the different minces on the left hand side, cardboard box of steaks and sausages right hand side, few small extra bits in the baskets at the top. If you were trying to store meat, veg, bread, etc it would be much more difficult to locate what you want when you want it, and I can see you'd end up emptying half of it out to fish out whatever you were after and then repacking it. If the chest freezer is your sole freezer then I'd invest in an upright for day to day stuff and use the chest for storing multibuys and longer term bits.