Hi Op, Hope this evenings been ok for you.
It really does appear (and of course what the bloody hell do we know based on a condensed 2 minute thread) that there is so so much going on for you at the moment, now really is a bad time to make a life changing decision! Please do wait out and not be hasty.
Do get utterly selfish. It doesnt have to be in a conflicting, cruel way towards your DH, but I do understand that, having spent decades of being the glue that keeps the household and everyone in it ticking over smoothly, youre at a time in your life YOU now need support......and no ones even a tad interested!!!!! Whilst its really upsetting and can sometimes seem to get out of proportion, sometimes those nearest to us arent the best placed people to help anyway. Theyre too close. or they cant understand why youre not the 24/7 superwoman youve been for as long as they can remember.
Set out a list. Everything that causes you anxiety, or hurt, or anger, or embarrasment any thing and everything thats going on. Then try to split the list into areas you may be able to address in small bite size pieces. Is the GP a good starting place for a couple of items? (dare I mention menopause, but theres no need to suffer in silence with that one these days....could it be youre possibly pre menopausal without realising it?) Are your iron/vitamin levels good? A good general health check is always a good start. Is there unfinished business from your old job? Are you having difficulty accepting some events that may have happened and find yourself having the same circular anxious conversations in your head? Do you feel stuck somewhere and not able to move on from something? Write all these things down. Are you anxious about the DC s? Anxious about the Uni move? Anxious that you may take on too much debt that you cant cope with?
Then of course theres DH. Perhaps taking time to just focus on you right now is absolutely the right thing to do. Sod what hes doing at the moment. If you focus on your list and how small things may improve your happines, then giving him a little list of subtle changes may help greatly. Could he make the meals a couple of times a week perhaps? Youve had decades of pushing the hoover round and ensuring the home is well homely, could saturday morning he join you for an hour or two, either helping with washing, or cleaning windows together, or sorting out that damn wardrobe youve put off sorting for 5 years, and then after that, his time is his own for the rest of the day?
Maybe youll feel comfortable sharing some anxieties you may have about finances or work or Dcs etc whilst hes showing willing to be part of Team Ginorwine for a couple of hours on a saturday morning.? IMO men are simple creatures. Give them clear, non-critical instruction, and theyre quite good at following, and if it makes you happy along the way...well double bonus time 
Im just throwing random thoughts around here, but most importantly is, put you first. Do that list.
After that make a list of what would you like to do that youve never had time to do before? Would you like to learn an instrument? Would you like to take up a sport? Would you like to sew, make your own clothes or craft, or make candles? (Have your own little craft room in a spare bedroom) Adopt stray animals? Breed chickens? Learn to ride and find a riding school? Join a hiking club? Cycle?
In short, if you were single...living in a little flat above the newsagents, what would you be planning to do this weekend? Do it now instead. If its going to stay with old friends for the weekend. Do it. Whats DH going to do? He'll be absolutely fine as long as theres a tin of beans in the cupboard.
Please no need to reply to any of this, it really is just a random brain dump, but hopefully maybe one or two little ideas may just help. And of course, share away on here if it helps too.