What do you consider high flying? I think DH has a pretty high flying career and he works less hours than I do. What I have found is that the more senior you are, there are so many more options for flexibility that are not there at the junior levels. I am suffering with this now while DH has broken through that level and now can go for golf twice a week with customers (who he is friends with) so doesn't golf at the weekend. He can pick his flights, set his travel schedule and decide which days of the week he will be in the office or work from home.
DH also has his own assistant. I am left booking my own travel, meetings and sorting the client out with billings that the Partner follows up on if they don't pay on time. It takes me 5 hours to get the bill created and sent to the client but the Partner spends less than half an hour following up on that bill that isn't paid.
A lot of high flying careers don't require more than 60 hours a week to get to the top. Over 6 days a week, if you live close to where you work, that is doable with good support and split shifts. In our case, DH goes in early and I come home late. Not sure if my career will be high flying. It feels like a lead balloon these days.