To ask if anyone else has heard that antihistamines can in some cases reduce the risk of miscarriage?

[BrightonMum36]

I remember reading about this a while ago, something to do with the antihistamines suppressing the body's over reaction to rejecting what it is perceiving to be a 'foreign' body.
I now can't seem to find this article and I've googled a few times to no avail. Has anyone else heard of this or even used this method to successfully prevent miscarriages?
Asking for a friend.
Thank you in advance... X

Google Dr John Smith at the Queen Elizabeth Hospital in St Johns Wood.
I read a similar article years ago but it was a hormone he used if miscarriage was occurring. A little bit disputed but he had a proven good record.

It's not exactly what you're asking, but an old style anti-histamine, cyclizine, is used to reduce the effect of severe nausea and vomitting in pregnancy.

A rather stronger version, promethazine, is also used. I believe there's a correlation between severe N & V and with successful outcomes of pregnancy .. though it's only a correlation or association.

Contrary to the perception left over from the awful Thalidomide experience, cyclizine in particular is medically considered completely safe (its sister anti-histamine in the states is the only med that is is Fed Drug Category A, meaning that it's considered absolutely safe).

Beyond that, well, people are cautious about meds for very good reason.

Do you mean Prednisolone?

It is a steroid that suppresses the immune system so that it doesn't attack and destroy the embryo as a foreign body.
It relates to the theory of 'Natural Killer (NK) Cells', which is a disputed area, but some fertility specialists and IVF clinics are convinced it is a very real cause of miscarriage and IVF failures.

news.bbc.co.uk/1/hi/health/4103884.stm

I remember reading about this, if you search for
natural killer cells miscarriage
you should get plenty of results

We found that some women's natural killer cells are so aggressive they attack the pregnancy, thinking the foetus is a foreign body

www.dailymail.co.uk/health/article-3177253/Couple-endured-heartache-six-failed-IVF-attempts-finally-three-healthy-babies-thanks-injections-soya-egg-yolk.html

As usual you brilliant, intelligent women have come up trumps with your invaluable help.
Thank you and I will use it for hopefully wonderful consequences! Xxx

I'll have to ask my mother what she used when she was pregnant with me. Our blood types didn't match and her body tried rejecting me, she had to get a shot for it.

Hard to get prednisolone prescribed on the NHS but not impossible. The treatment also goes with daily over the counter aspirin and intralipids infusions given at four weekly intervals. A side effect of prednisolone is that it can cause annovulation when taken before ovulation so only started taking it after positive result. Currently 8 weeks pregnant with dc2. Good luck!

bulbs you weren't your mum's first pregnancy? It is probably Rhesus negative which happens with subsequent pregnancies when the mother has a certain blood type