My parents moved me and my brother 250 miles down south when I was 13 and my brother was 14. I was happy to move for all of 6 weeks, until I started school in the middle of the school year, no friends, different accent, got bullied quite badly, and we left my eldest sibling back up north. 
This was all to give us better employment opportunities, and to give my father a better chance at finding better paid work.
My brother changed his accent and tried hard to fit in, and as a result, he made some friends and says he was not bothered about the move.
Interestingly, neither my brother nor me have ever managed to get a good job, and have both remained in minimum wage jobs. (Our education was disrupted due to moving at that age imo).
My parents divorced within 4 years of the move, my father had no relatives down south, yet he now earns £7K a week, and my mother only ever found minimum wage work, and is now miles away from her siblings and has no family support apart from me and my brother.
At the time, I thought their reasons for moving so far away weren't enough to warrant a move that far, and the loss of the support of family and friends.
I haven't changed my stance on that, and as a consequence have only moved once in 21 years. I could not move my DC away from their school/friends/family while they were at school unless it was a case of being unable to survive where we were.
My parents were able to survive where we were, and never did end up better off, it was all a dream, which unfortunately turned sour.
If I had to choose between feeding my DC and moving, as opposed to staying put and struggling to pay essential bills, I would move, but if, as in the case of my parents, it was to move up the housing ladder, and to be better off financially, I would wait.
I do believe my parents made their decision based on what they thought would be best for us all at the time, but it's nigh on impossible to know what living so far away will be like before you have actually moved imo.
I'll stay on the safe side for as long as possible.