When I first had DD it took me a long time to adjust to being needed so much IYSWIM (I generally really like my own space!). Being on the go all the time - feeding, changing, comforting....
Then when I had DS, it took me a really long time to adjust to having to have eyes in the back of my head, five pairs of hands......
Now DD is 5yo and DS is 3yo, and it just never ends. I haven't stopped all morning. Emptying potties, answering incessant questions, breaking up fights, cleaning up mess, comforting, reprimanding, repeating myself, etc etc etc etc. Same as any other parent I'm sure. It's like this until bedtime (unless the telly goes on!).
So do you EVER get used to it? I keep feeling like it's got a bit easier, and then potty training starts, or DD goes through a dramatic or emotional phase, or DS starts tantrumming!