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Migraine prevention battles

29 replies

Pinkysavestheday · 12/06/2026 09:46

Hi, apologies in advance for long post but at a loss how to proceed with migraine prevention and hugely appreciate anyone else’s advice/ experience. Suffered for over 30 years and finally went on first preventative last September following a non-stop 7 week daily migraine. Amitriptyline reduced that to an average of 10-12 migraine days/ month which is huge for me. Unfortunately had to keep increasing dose to maintain effect and once I’d been on 75mg for several months, stopped being as effective again and heart rate started being impacted, so tapered off 5 weeks ago. Tapering was fine until the the last week (so 6 weeks ago) and sleep stopped and started feeling pretty sick. Then started on 80mg standard release propranolol 17 days ago. Have barely slept since and been back to daily migraine for two weeks. Have follow up with doc in another two weeks. Also had 5 auras in last two weeks, which I don’t normally get. Do I keep going as I know these things take more weeks than I’ve tested the propranolol for and it could also be that I need a better dose?. Could it also still be amitriptyline withdrawal and I’d be daft to have got this far with a new med and to give up too soon. See a long stretch of three steps forward, two steps back ahead. Not sure I can maintain my job indefinitely! Help please!

OP posts:
Paddingtonridesagain · 13/06/2026 13:13

I do think that body weight makes a difference. I also have low weight and feel an 8 stone woman must surely need less than someone of 16 stone?
I also believe that most migraine sufferers are highly sensitive to medication.

I am on Ramipril but it does not affect my migraines.

Paisifr · 13/06/2026 13:24

Have you contacted the migraine trust? I found them to be very helpful. I’ve also found acupuncture helps with mine particularly as stress is one of my triggers

MyKindHiker · 13/06/2026 13:55

Watching with curiosity.

i really wanted to try topiramate (probably spelled that wrong) but wasn’t allowed because i am of child bearing age even though i have 2 kids and husband has had vasectomy.

OP i think anything is worth a try as everyone responds differently to different meds. For every person I know who’s tried it and it’s been awful I know another it’s been life changing.

Also - hugs. I get maybe one migraine a month (auras more often - mine involves getting words jumbled which is not good at work) and even that is too much.

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Purpl · 13/06/2026 14:28

Also aura only numbness and no pain for 5 days at a time. I saw a neurologist privately and he recommended 4 x b2 tablets & co_enzyme daily for at least 6 months and it really helped plus the daith piercing gives me bacj my eyesight in 8 hours but still feel bad for 5 days.

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