Intense random gut pain, had anyone had this?

[BrightLemonSnail]

I was on Mounjaro for 6 months. First month I lost 1.5 stone then no further loses, so I quit (since put it all back on). In that time on Mounjaro I had 3 very intense gut pain episodes. They come on from nowhere are a 10/10 on the pain scale, I could hardly breathe. They last about 20 minutes then go, leaving a tender tummy afterwards but nothing too bad. The very first one lasted about 5 hours though and was the worst thing I ever experienced. I put it down to Mounjaro. However after stopping Mounjaro about 3 months ago, I've had 4 more attacks. One yesterday and one today. Sudden onset, 10/10 excruciating pain and I can do nothing but lie down, strip as I get so hot, and howl. Then it passes after about 10-15 minutes. Passing gas and no.2 give no relief. I booked in with the GP and have 2 weeks left before the 6 weeks it took to get an appointment. I had an ultrasound about a month into the Mounjaro to check for stones after my first attack and my gallbladder was clear, no stones or sludge. So I'm at a bit of a loss what's causing it. I expected it to stop after the Mounjaro but it's months now and getting worse. Has anyone had anything like this?

Gallbladder?

Look up abdominal migraines?

It sounds like gallstone attacks to me. If the stones are small they coild have been missed in an ultrasound, if it was me I’d want to get another scan (private if necessary if nhs refuse another) and bear in mind gallstones can be really REALLY tiny. I was advised that the tiny/ small stones can cause a lot of problems as they are highly mobile and prone to getting stuck (in the neck of the gallbladder or bile duct).

Were you offered a blood test ? It's likely fall bladder but equally I would want my pancreas checked .

Gallstones is common with this sort of stuff OP. I was scanned for gallstones in 2016 and told it was clear. In 2019 at my preop the nurse told me cheerily that is had gallstones since 2016.

Those jabs also affect your pancreas as well. It might be worth thinking about if it's worth it or not.

Sounds like gallbladder pain xx

Gallstones. I had this. Got it checked. Said it is billary colic. Didn't need it removed though as so small.

MRI is better than ultrasound for assessing the gallbladder I think (I am not a doctor, but had an MRI after an ultrasound failed to show a problematic stone stuck in the duct). Your post does scream ‘gallbladder disease’ to me I’m afraid. Can you afford a private consultation and MRI?

I had this a few times years back when doing low fat diet........researched it myself (medical background) and decided it was biliary colic. Found that you need about 10mg of fat per meal for the bile to be expelled so probably sitting there turning to sludge (sorry not very scientifically put☺️). I started to ensure i had that much fat each meal and never had it again.

The most excruitiating pain I've ever had and had three babies without pain relief, honestly made me frightened to continue dietting. Advice online was to take ibruphren as soon as felt it coming on for its anti inflammatory effect which helped but abdomen was very tender and uncomfortable for couple of days after each attack.

If it's towards the right rib area it's gallstones. If it's central and goes through to the back it could be pancreatitis which is very serious. They can test for this with a blood test.

Thank you all. I've booked a private abdominal ultrasound scan for tomorrow morning. I'll explain about the attacks. It's concentrated now under my right rib, a full, aching feeling after this afternoon's attack. With any luck I'll have some answers this time tomorrow 🤞🏻

Gallbladder pain can be central also. I've just had the blood tests for pancreatitis after a similar attack, and they think gallbladder may be more likely even though the majority of the pain is central.

How high or low is the pain? Closer to the belly button or boob level?

It's in the middle between belly button and rib cage, across there. It hurts to breathe when it's happening, so diaphragm area. Taking a full breath is agonising. Going on one side or the other doesn't bring relief. It's never been in my back, shoulder, jaw etc though. Now it's just sore under my right rib from today's attack, kind of like an overinflated balloon there.

Does getting on all fours on the bed give any relief at all? Put your head down low and your bum high in the air. If yes it sounds a lot like gallstones. You feel like a tit doing it but it does help. Having something pressed hard into you like leaning on an ottoman can help too. Glad you have a scan booked in either way.

Gallstones, 100%. An overinflated balloon is exactly how I described it too. They are very common after rapid weight loss.

I had similar whilst taking Mounjaro and blood tests showed my amylase and lipase levels were elevated which according to my GP points towards pancreatitis.

I’ve had a few episodes since coming of Mounjaro but my last blood tests were nearly normal so I’m hoping my GP was right when she said it could be short term inflammation.

I think that sounds quite classically like gallbladder pain. However, I get a very similar pain, though lasts like seconds, it’s like being stabbed just under the right rib cage. I have a problem with my pancreas. Now my gastroenterologist has never said that it’s the pancreas causing the pain, but I never had it before I had pancreatic issues and it was certainly more common when my pancreas was more inflamed than it is now. I certainly think it’s related in some way. I’ve never been told I have any gallbladder issues and I’ve had an awful lot of abdominal ultrasound/CT/MRIs over the years.

Gallstones are very common with weight loss, not just the WLI. I’m currently going through the same thing and I’ve had a scan that confirms gallstones.

An update. Just had my private ultrasound and yes my gallbladder is full of stones both large and small. Sigh. At least I have answers now.

Ah. I’m sorry you have gallstones, but glad you have an answer! For what it’s worth, I honestly found the surgery to be ridiculously straightforward and easy to recover from. While you’re waiting, try going as low fat as you can possibly go - I didn’t eat anything that was more than 3% fat. Incredibly restricting (and not healthy at all in the long run) but I didn’t have any attacks in the months between diagnosis and surgery.