Type 2 diabetic here.
Facts:
I'm on Ozempic (wegovy/semaglutide)
Prior to Ozempic I was on other similar drugs (tablets and injections, empagliflozin and liraglutide)
I've lost 30+kgs, from well over 110kgs to about than 70kgs.
My take on this?
Ozempic made me feel really, really nauseous. This pushed me into changing my diet drastically, so that I now eat a lot more easily digestible food I did before, so fruit, veg, eggs, fish. I also eat a lot of high calorie foods because I was losing weight too fast, but it was small portions to avoid the nausea.
It's also changed my eating habits dramatically. I eat a lot more fruit and veg, my calorie intake comes from high-value calorific foods (I eat butter, cream, full fat cheese, rather than "light" foods). This has also resulted in my cholesterol results being much improved (overall cholesterol is down, good cholesterol is up, bad cholesterol is down).
The medical professionals that I've talked to have all agreed on one thing. Ozempic, etc, works primarily because some people have a defective gene that switches off the "I'm full" hormone (60% of labrador dogs have the same problem apparently). Switching on the (glp1) hormone fixes that problem. They cant explain the nausea (at least the nausea before eating, whereas the nausea during/after eating can be put down to overeating). But counteracting the nausea, by eating the easily digestible food and stopping the overeating, works towards weight loss.
It's not a miracle cure, I've started gaining weight again after 2 years of weight loss. But my hba1c (if you're diabetic you know what that is, for everyone else its the highly important measure of blood sugar that us dbs need to keep track of) is holding steady at 51, and has done now for 18+ months. GP has moved me from 6 monthly checks to yearly checks. Overall my metrics are vastly improved and my diabetic specialist nurse and my gp are extremely happy with my progress.
I'm on Ozempic for life probably. For anyone looking to lose weight you would probably not want to be on it more than 2 years (read up on the side effects) and so you should develop new eating habits that you will be able to sustain once you move off it. Though from my experience 2 years seems to be the weight loss limit anyway. I'm on it for the hba1c results anyway not the weight loss.
Please dm me or reply here if you have questions, I will do my best to answer
Go well xx