I know I'm very lucky to have it available. But I hadn't realised it was just so much trial and error. I'm in probable perimenopause, and different symptoms come and go horribly whether I'm on HRT or not. Don't know whether to up or lower the dose at any time. The same signs can be related to too high or too low of different hormones. No one can tell me much to guide, apart from "try it". It's mayhem. Anyone else feel the same?