Anyone using progesterone vaginally if it gave you crashing low moods orally?

[Loggingin]

I'm peri and started HRT last Oct. The progesterone tablets (ugesterone white gel capsules) have given me devastating low mood and crashing despair for 2-3 days a month. Doctor is suggesting trying them vaginally.

Just wondering if anyone else has experienced this and if switching to vaginal use was helpful?

I tolerate them better vaginally, seems to bypass many of the side effects that way. Definitely worth a try.

Me too, much better mh when taking it vaginally. One capsule instead of two as well, so a box lasts 2 months / cycles.

@paranoidmumdroid1 did your GP advice just one tablet? Mine said you can use 2 or 1, which sounded a bit vague.

I have been fine on progesterone for a while and have been taking 1 tablet continuously. However, recently I’ve had very low moods and anxiety. One day last week I was just sobbing all day.

I spoke to my doctor and we agreed I could try them vaginally after she had checked the British Menopause Society website. She has told me one a day but on the Louise Newson site it says to use one every other day. I’m currently going with what my doctor says but am unsure. Although I know it’s really important to get enough progesterone so the womb lining doesn’t thicken. She couldn’t tell me if it was safe to have too much though😕

I spent 2w a month believing the world would be a better place without me in it when I was in utrogestan. It also made me bleed so vaginal wasn't an option.

I switched to patches and now I'm totally invincible for those 2 weeks. The other 2 weeks are tolerable - but definitely better than the urtrogestan weeks!

There's bound to be a way that works for you!

Yes - I switched to taking one tablet vaginally from two orally
. I'm doing that two weeks out of. Four. But I think that's because I'm still having periods. But they are disappearing so I think I'll be moving onto every other day at some point

UPDATE

Started to bleed after a few days on one utrogestan vaginally. Also suffered with horrendous cramping. Back to taking it orally now 🙄

OP, I still had all the side effects vaginally, but also thrush.

Utro made me so utterly depressed for at least 2 weeks a month.

Switched to mirena and it's so much better. No crying. Sleep like a baby. Some small side effects like tiredness and headaches but a million times better than utro.

Yes - it was a miracle cure!
That was a few years ago. I am struggling again now though which I think is due to lower levels of hormones

And possibly tricky teen years of my kids if I'm honest

Two tablets orally became 1 tablet vaginally

Hi I know this is old but did this work for you ? Iv had the same reaction to progestone orally

Does anyone know if this is possible with combined pill HRT? I know you can take oestrogen locally using Gina so I’m guessing it might be safe but would it be a case that the oestrogen isn’t then absorbed so systemically?