It depends on your budget and whether he has a car.
Stretford is OK and near to where he works. Safe middle / working class area with a good community but not very chi chi and in need of development which is happening now. No obvious centre to Stretford. Near the tram would be good call. Look near the arndale centre.
In town: Ancoats, castlefield, middlewood basin/locks, Salford on the irwell near spinningfields. All pricey. I'd love my kids to be able to live round ancoats when older. Bad to live in town if you have a car as a place with a parking spot is pricey.
Salford quays very nice. Also pricey. Bit soulless. Same problem as town for parking.
Some of the juniors who work for me live in Eccles or Irlam to save money. Eccles is on the tramline. Irlam just bus and train into town. Eccles not far from m15. I think eccles is a dump and not very safe. Irlam just a bit unexciting but a decent place. Better if you have a car for Irlam.
I lived in chorlton in my youth. Its got loads of bars, on the tram, kind of urban cool rather than chi chi. I loved it. I still live nearby. They're digging up the crossroads at the moment. Bloody roadworks everywhere. Including Stretford.
Firswood is a non-area right on edge of chorlton bordering old Trafford so would be near enough to work. Tram stop and easy to get into chorlton or town.
Whalley range is next to chorlton and not too far from old Trafford which is probably near his work. It's the chorlton overspill. Large houses where he could rent a room on wide tree lined streets. Very down at heel, mix of asian area and middle class white overspill from chorlton. Actually not a bad call as you're near town, his work and chorlton for a night out if you look around near the chorlton border / Seymour Grove Way rather than the other end near alexandra Park.
I'm not mad keen on old Trafford, I'd avoid. Cricket and football make it a PITA and its not great for youngsters.
I live in Urmston. I'd recommend it for families but its got a few bars and is a nice place. Train to town or bus. Parking better.
Sale is also further away from M15 also on the tramline. Great area. Very middle class. Lots of bars nowadays. Parking a nightmare. Probably not a bad area for younger people but its not an obvious choice.