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Anyone around who can read medical records?

6 replies

lifekeepsgoing · 12/06/2023 17:52

Sorry if this is not the appropriate place to ask this question but I just wondered if anyone is around who can read medical records and know what "ER and PR and negative" means?

I am trying to determine if my mother's ovarian cancer was estrogen positive or not. I need to get the information before my doctor will prescribe HRT. I assumed I would just get the information but instead I have received all her medical records and I am trying to make sense of them.
I think that the information below means that the cancer cells were estrogen negative but just wondered if anyone more knowledgeable might be able to offer any insight? Googling suggests that "ER and PR and negative" means negative for estrogen.

"InterpretationA. Right ovary - Immunohistochemistry has been performed which reveals strongand diffuse positivity of the tumour cells with P16 and P53 (mutational typestaining with P53). ER and PR and negative in the tumour cells (Quick score of0/8 for ER and PR). WT1 is positive in most of the tumour cells. SMA isnegative in the tumour cells.MYO-D1 is positive in a few scattered cells within the sarcomatoid areas"
Thanks for any insight anyone can share.

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KTSl1964 · 12/06/2023 17:54

Can’t help but is there a medical thread?

altmum · 12/06/2023 18:00

It means immunohistochemistry has been performed and the tumour cells are negative for both oestrogen and progestegen receptors. Is that what you were asking?

lifekeepsgoing · 12/06/2023 18:02

Thanks so much altmum, yes my doctor asked me to find out whether my mum's cancer was oestrogen positive or not and I am trying to figure out whether it was or wasn't from pages of medical records that I applied to get access to.

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Greybeardy · 12/06/2023 18:35

Your doctor will be able to interpret the report if you show it to them.

Squirrel28 · 12/06/2023 19:19

The Quick score is a combination of the proportion of cells which are positive for ER and PR and the intensity of the staining - so Quick score 0 means no tumour cells are positive and there’s no staining at all (ie unequivocally ER and PR negative).

lifekeepsgoing · 12/06/2023 21:10

Thanks very much Squirrel and Greybeardy.

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