A few examples:
My mum died at 53, she'd always been big as long as I remember, she couldn't walk far or run like other mums could when we were children. She died when I was 26, fortunately I had been to uni, was married and had a 2, nearly 3 year old by the time she died so she saw me graduate, get married and experienced becoming a grandmother. In the final 5-10 years she became incontinent, constantly infections so always on medication..she had asthma, angina, high blood pressure, diabetes, fatty liver disease, very poor health. She has heart failure in the final year or so, heart attacks and finally a cardiac arrest. My sister was with her when it happened, her body lurched, she fell off her bed, hit her head, couldn't be moved. Paramedics managed to get her heart beating, she went to ICU, but as a result of her brain being deprived of oxygen for so long she was brain dead. She needed an bigger casket and her coffin couldn't be carried, but only transferred to a stretcher due to the weight.
My childhood best friend's mum was 30 ish stone, could barely walk, without being in substantial pain, lost a lot of weight, down to 14ish stone, went into hospital to have medication changed, developed bed sores that developed into cellulitis, which led to bone infection. She wa in hospital for years 2012-2016, then to a care home, the infection to her bones, affected legs/circulation due to diabetic nerve damage and she ended up having a leg amputated....needed help going to the bathroom, cleaning ect, constant infections and looked like the other leg was going to be amputed died before 60...bed bound, and having her own children clean her/empty commode ect