I think that's a really hard question to answer in an objective way, since it depends on your life situation, and preferences at that time. I lived it the west coast US for a number of years, enjoyed it, had much more disposable income, but was happy to move back to England to be close to home (in Northern Ireland).
I also lived in Dublin for a few years, that was OK too, especially with respect to great work opportunities, and schools for kids.
I'm back "home" in NI now. It's a lovely scenic place, property prices so much better than England & Dublin, overall much less busy and relaxed lifestyle. However, lots of people would hate where I live due to risk of "troubles", rampant sectarianism (strong traditional unionist heartland), but it does not bother me on a day-to-day basis and I've no great interest in NI politics. I love it, because it is home, and I'm aware of the pros/cons having lived in a few different locations.
If you are super unhappy, there is nothing to stop you taking a risk and trying it! That's what we did! You might find something you like a lot more, and the distance might also appreciate some of the things you have today.