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Difference between CKD and AKI with no treatment.

4 replies

WishIWasSomewhereElse · 11/05/2021 18:00

Short background: My dad had primary Kidney Cancer and Primary Bladder Cancer. Bladder treated easily, Kidney required a nephrectomy then Pazopanib after Mets to the aorta.

At the end of last month he was diagnosed with Primary Pancreatic Cancer after what they thought were side effects from the Paz - NOT Mets from the kidney, but a new primary cancer in the pancreas. No treatment was forthcoming and the Paz was stopped as his KC would not grow to fatal sizes before the PC succeeded, so for quality of life all treatment has stopped.

He was straight in hospital due to worry over PE, this was ruled out. However his kidneys proved to be a concern.

He already had stage 3 CKD (predating the KC), diabetes and COPD. He was discharged from the renal unit as his kidney function had improved to such a level, that it no longer required monitoring.

On his notes it says he has AKI. I know this stands for Acute Kidney Injury, and that it relates to loss of kidney function in regards to existing or new illness and not a physical injury to the kidney, but am not sure how this differs from CKD? They note he has CKD, but that the AKI is new.

He spent the day in hospital again today, to check his kidney function had improved - it hasn't. The doctor said it would be too invasive to try to find out what has caused it and to basically keep him happy and give him lots of liquids.

What exactly does this mean? Is there no treatment?

OP posts:
WishIWasSomewhereElse · 11/05/2021 18:34

Anyone?

OP posts:
WishIWasSomewhereElse · 11/05/2021 19:23

Hopeful bump, in case someone medical might see.

OP posts:
NicAndNick · 11/05/2021 19:23

AKI is a generic catch all for short term worsening of kidney function. It can go on to become permenant worsening of kidney function. As it is a catch all the causes can be many and the treatment would depend upon the cause. For an example dehydration could cause it, but so could a kidney stone blocking the outflow and both causes would have different treatment.

So I would say that your dad has long term kindey impairment, now his kidney function tests show worse than his background level over a short period of time, rather than a long deterioration. I hope that makes sense and answers your questions.

It sounds tough, my thoughts are with you Flowers

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WishIWasSomewhereElse · 11/05/2021 19:49

Thank you. He was on a drip for five days last week and a drip today, but none of them have improved it to any extent. It makes sense what you say.

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