I'm 2.5 hours away if there is no traffic getting out of my city and on the motorway to half way (so usually more like 3+ hours). (After halfway is still motorway mostly but not congested normally so higher speeds are normal).
We are here 22 years now (well, this city - we've moved around the city a couple of times). DD is 14. DFIL died 6 years ago. DMIL and DPs are all in the "not terribly elderly but retired and all have medical issues of sorts". But there are siblings on both sides near them (some more reliable than others for daily or emergency needs). But as the eldest on both sides, we both have pangs of guilt applied to us, and that we put on ourselves. (DPs and DMIL are only 20 minutes apart by car).
We both had jobs here, DH came back from overseas for his, I initially had one here as the only one I got leaving Uni (having gone to Uni in the city nearest DPs/DPILs) and then got my permanent role in another area also in this city. Neither of us could have the same job "down home".
And we are settled here and like it here.
We had travelled down home a lot more in earlier years, when we were more free and easy. But now have too many commitments at weekends to go often. But when DFIL was ill, I got very used to driving DD and I down every weekend and managing that alone (DH spent most of that 6 weeks down there WFH or travelling from their airport rather than here). We have often done it in the one day for special events if we couldn't do a weekend etc (down in the morning and home that night). We keep in touch frequently by phone and now zoom etc.
We would have a completely different life down there, which I don't think would be anywhere near as fulfilling as what we have here. We have made good friends over the years, through work and other activities. Usually going "home" is more about meeting family than seeing old friends (TBH most have relocated away like us, a few are near us here but lots are scattered around the globe).
There hasn't been the practical support of DGPs when DD was young, but I don't know that we would have had it even if we were near them "down home" - we still would have been using external care (but probably a childminder rather than creche, based on what's available there). But they have taken her on occasional weekends in the past and we've been able to have a break. And there are good babysitters available near us so we can still go out when we want to (we're not the most social of creatures so it's the odd dinner or movie, rather than weekly clubbing).