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AMA

MNHQ here: AMA with hormone specialist and leading voice in transforming hormone healthcare worldwide Dr Louise Newson

94 replies

RhiannonEMumsnet · 29/05/2026 14:47

Hi there,

We’re delighted to announce an AMA with GP, hormone specialist and leading voice in transforming hormone healthcare worldwide Dr Louise Newson on Wednesday 3rd June, 7-9pm.

Dr Louise is an award-winning physician, educator, podcaster and author, committed to increasing awareness of hormone health including perimenopause and menopause, PMS and PMDD. She is also founder of the free Balance hormones and menopause app.

Dr Louise is currently in the midst of a nationwide live tour Breaking the Cycle: The Power of Hormones, where she unpacks the history of hormones and reveals how decades of misinformation and medical misogyny have harmed the health of women – a topic also covered in her new Sunday Times Bestselling book, The Power of Hormones.

Please post your questions for Dr Louise below and join her on the thread on Wednesday evening to hear the answers.

As always, please remember our guidelines - one question per user, follow-ups only if there’s time and most questions have been answered, and please keep it civil.

Thanks,
MNHQ

DramaQueen1970 · 03/06/2026 19:41

Many thanks for your reply Louise, I really appreciate it. So much of the advice given by gynaecologists seems to be outdated.
My original prescription for the Lenzetto spray and Utrogestan was tailored to allowing for a bleed. If I continue to have no bleeding (I now believe it was related to the fibroid and not a period), do I take the progesterone continuously now with the break ?

DrLouiseNewson · 03/06/2026 19:42

GladJadeHam · 03/06/2026 19:22

Hi Dr Newson , i have been presxribed utrogestan continouosly depsite im in peri becaus on going bleeding , but when i take it beofre bed it make me awake hour or twonkater why is that ? If i take if during the dau i sleep better . Had appoitment at your clinic and it was the best !

@GladJadeHam glad you had a great experience at our Newson Clinic. You can take Utrogestan at any time of the day. Magnesium can also help with sleep too

Experts' posts:
DrLouiseNewson · 03/06/2026 19:43

DramaQueen1970 · 03/06/2026 19:41

Many thanks for your reply Louise, I really appreciate it. So much of the advice given by gynaecologists seems to be outdated.
My original prescription for the Lenzetto spray and Utrogestan was tailored to allowing for a bleed. If I continue to have no bleeding (I now believe it was related to the fibroid and not a period), do I take the progesterone continuously now with the break ?

@DramaQueen1970 yes that is usually what is recommended. Many doctors seem to be giving outdated and inaccurate advice to women which is so sad

Experts' posts:
DrLouiseNewson · 03/06/2026 19:45

Ritaskitchen · 02/06/2026 07:29

Hi Dr Louise, In many countries women have access to a Gynecologist as they would a GP in the UK. The gynecologist does a yearly exam and is seen during pregnancy and post natal and deals with contraception etc.
Why don’t we have this model in the Uk? Are there historical reasons for this?

@Ritaskitchen actually often GPs have far better knowledge and experience about women's hormones than gynaecologists - after all, our hormones are made by our brains as well as by our ovaries so it makes little sense that gynaecologists are often controlling women's hormones!

Experts' posts:
glowfrog · 03/06/2026 19:47

DrLouiseNewson · 03/06/2026 19:27

Many women take progesterone each day which is better for them, also it may be worth you having your oestradiol levels undertaken to determine if you are on the right dose for you. Testosterone can also improve mood and other symptoms.

Thank you, much appreciated.

DrLouiseNewson · 03/06/2026 19:47

MichaelmasDaisiesAndAutumSunset · 02/06/2026 07:52

Hi, I have struggled with my hormones all my life (I'm 44). I have had 5 rounds of IVF (last 4 years ago) and have three children. I have significant PMDD (medicated with sertraline and pregabalin) and this has been from my teenage years. It has now been suggested that some of my symptoms are caused/exacerbated by MCAS (I am also hyper mobile, which I think has contributed to this thinking). I am currently failing at the elimination diet to test that.

I have tried everything: diet, HRT, supplements, Nettle device, and yet again a week before my period I am struggling not to blow my life up. I'm exhausted, and I don't know what to do. Any suggestions? Thank you.

@MichaelmasDaisiesAndAutumSunset I am sorry to read this. Has anyone tried progesterone (Cylogest) with you? Natural, body identical hormones can be really beneficial for women with PMDD and many women who struggle have low progesterone. This article may help you - PMS and PMDD: get treatment that’s right for you: https://link.balance-app.com/content/MxUesBzbibSnsgyiwjPIa6

Balance

Balance - Menopause support, symptom tracking, and expert-led content.

https://link.balance-app.com/content/MxUesBzbibSnsgyiwjPIa6

Experts' posts:
DrLouiseNewson · 03/06/2026 19:49

glowfrog · 02/06/2026 10:31

I hope it’s ok to ask 2 questions. I forgot to mention that when I try to take the progesterone capsules on an empty stomach, I feel woozy and like I’m going to pass out. So I’ve been taking it before bed, and sometimes that means it’s not on an empty stomach. Could that explain my issues?

Lastly - I’m still sleeping badly - waking up twice a night and sometimes struggling to get back to sleep. As a result I feel constantly exhausted. I sleep better when I take the capsules. Is it indication I should take more, or…?

Better sleep would be such an improvement! I long for the days when I might wake up feeling rested.

You can take Utrogestan when you have eaten - it just means that more progesterone is absorbed into the body which actually may help you to sleep better. Some women take 2 progesterone capsules at night which can improve their sleep more - it would be worth you talking to your doctor about this.

Experts' posts:
DrLouiseNewson · 03/06/2026 19:52

Sesame2011 · 02/06/2026 10:40

Hi Dr Louise, im 38 and 10 months post partum with first and only baby. Im still breastfeeding although not loads, and my period returned at 4 months post partum.

During the first 2 days of my period, my mental health plummets, sometimes I cant get out of bed, im planning my divorce and escape from the house (which i dont plan otherwise and am happy when not pms'ing) and really struggle to work. Is this normal and am I expected to just deal with it? It wasnt this bad before pregnancy. My skin has also been horrible since 1 week post partum although eased off around the 8 month mark.

Edited

@Sesame2011 I am sorry to read this - it is likely that your hormone levels are low on these days. Many women find that taking natural, body identical oestradiol and sometimes progesterone really improves symptoms and may only be needed on the days you have symptoms. It is safe to breqastfeed with these hormones as they are just natural hormones - so the same structure as the hormones you are already producing. Very different to synthetic "hormones" in contraceptives.

Experts' posts:
DrLouiseNewson · 03/06/2026 19:55

JacCritter · 02/06/2026 13:24

Hi Dr Louise
I recently noticed that nice had approved Fezolinetant as a non hormonal alternative to hrt. I am 59 and had oestrogen and progesterone driven breast cancer in 2019 with a lumpectomy followed by a dual oophorectomy in 2020. Since 2021 I have had abdominal pain which various pain consultants have diagnosed as anterior cutaneous nerve entrapment syndrome (ACNES), following the 2021 laparoscopy. I have had multiple nerve blocks, electricity has been driven down the nerve, etc. etc. to no effect, and Guys has now discharged me from their pain clinic as there is nothing more they can do. I am back on the gynaecologist waiting list for a full hysterectomy as a last resort in the hope they can patch up the adhesions while they're at it. Plus I have a 46 year history of endometriosis and have now discovered that endometriosis can continue post menopause.
Anyway after that ridiculously long history, I have been taking venlefaxine for anxiety for about 3 years, as one gynaecologist recommended that it would cause less sweating than sertraline. In fact the sweating with venlefaxine is much worse and combined with the menopause is horrendous. Venlefaxine apparently is useful for nerve pain however, and despite trying 3x to switch back to sertraline, the pain breakthrough is too much. Have also tried duloxetine which is little different to venlefaxine.
I have asked my GP about fezolinetant but it is so newly approved by Nice that she has referred the question to the gynacology department and I haven't heard back. My question would be, will fezolinetant start the endometriosis off again, while I'm waiting (about a year apparently) for the hysterectomy, and can I be prescribed it with my breast cancer history? Will it be effective for venlefaxine driven sweating as well as standard menopause hot sweats?

Sorry for such a long and involved question and thanks in advance for any help you can offer.

Jacky

@JacCritter sorry to read this. Just because fezolinetant is approved by NICE it does not mean it is safe - there are some concerns about this drug and it may increase incidence of cancer in some women. Some women do take hormones after breast cancer - we have published data on women who have had breast cancer taking testosterone after breast cancer and many of their symptoms have really improved. These are articles I have written about fezolinetant - New fezolinetant paper raises key questions: https://link.balance-app.com/content/nUufOMKqYmjdcxNmGdo7B7
Why hot flush drug fezolinetant isn’t the answer: https://link.balance-app.com/content/omxWC0Rj53FutAqkzpeYjl
Fezolinetant for hot flushes: https://link.balance-app.com/content/5GRhNlyon5cfKSCgZMPu1D

Balance

Balance - Menopause support, symptom tracking, and expert-led content.

https://link.balance-app.com/content/nUufOMKqYmjdcxNmGdo7B7

Experts' posts:
DrLouiseNewson · 03/06/2026 19:56

Summerhillsquare · 02/06/2026 13:47

Have you come across patients with oestrogen intolerance ie it makes their symptoms worse?

@Summerhillsquare Prescribing hormones is very individualised. Some women need progesterone and testosterone before oestrogen - if you feel worse on oestrogen it may be because the balance of your three hormones is not right so it would be worth you seeing a doctor who is really experienced in women's hormones.

Experts' posts:
ElliePhant28 · 03/06/2026 19:57

Hi Louise I use a weekly 50 patch and mirena. My symptoms were (only) headaches, I don’t flush, don’t have problems sleeping etc.

I feel like my breasts feel quite full and period- like swollen on 50 mcg, so am wondering if I should reduce the dose or use half a patch to see if it has any impact on bringing back the headaches. There’s history of osteoporosis in our family so I don't want to completely stop.
I’ve had Mirena for about 7 years and been on estradiol for about 5. What would you recommend?

DrLouiseNewson · 03/06/2026 19:58

Sorrel212 · 02/06/2026 16:04

Hi Louise,

Thank you for everything you do I have learnt a huge amount from following you over the last couple of years.

My question is about managing PCOS and PMS in a 15 year old girl. She’s tried several different contraceptive pills, Dianette helped her acne loads but it gave her awful low mood and anxiety so she had to come of it. Yasmin didn’t really help her acne and gave her low mood, Microgynon made her acne worse and also gave her low mood.

We’re certain that trying pill after pill is not the answer! But what is the alternative? The GP just keeps offering different contraceptive pills (she’s not sexually active it’s purely for her acne and to give her a bleed)

We just feel so stuck, is there anything else we can do / try please?

@Sorrel212 this is really hard - I have written a lot about the synthetic hormones in my new book "The Power of Hormones" which is worth a read. Many teenagers and young women have low progesterone in their bodies so really benefit from taking progesterone (such as Utrogestan) which is much safer than synthetic "hormones" which actually block natural hormones working

Experts' posts:
DrLouiseNewson · 03/06/2026 20:00

Relaxd · 02/06/2026 16:38

Hi Dr Louise. I take daily hormones (combined pill and a high dose of Norethisterone) due to thoracic endometriosis, will this mask or amplify perimenopause, or not affect it? Thanks

@Relaxd there is a lot of information about endometriosis and hormones on my Balance app - Balance app https://balance-app.com/

Many women with endometriosis are so much better with natural progesterone and natural testosterone (many women with endo have low testosterone) and some benefit from estradiol too. These are VERY different to synthetic hormones you have been taking. I would suggest you see a doctor who really understands hormones - we see many women with endometriosis in my clinic.

Balance

Balance – Menopause & Hormones

https://balance-app.com

Experts' posts:
DrLouiseNewson · 03/06/2026 20:03

ikeepforgetting · 02/06/2026 16:44

Hi Louise, is there evidence that testosterone supplementation can help with muscle and joint aches? I am 52 and on HRT for 5 years - currently 3 pumps gel and 1 Gepretix every night. I have started to have painful joints and nothing shows up on blood tests. I wondered about either more gel (but concerned about womb lining) or testosterone, any advice?

Edited to add that I do not get along very well with progesterone!

Edited

@ikeepforgetting yes there is good evidence that testosterone improves muscle and joint pains - it really reduces inflammation in our bodies including in our muscles and joints.

Experts' posts:
DrLouiseNewson · 03/06/2026 20:05

hushabybaby · 02/06/2026 17:07

I breezed through perimenopause, but as soon as I was in menopause it was hell! Dizzy, low blood pressure, had to start eating every 3/4 hours, lost weight, low energy, raging anxiety!
6 months later and I started Estradot Conti 30/95.
After only 5 days i feel so much better!
I have been to my Gp several times, of course he prescribed sertraline which I didn’t want and had to go private in the end. To this day he still hasn’t prescribed HRT for me via the NHS.
Mainly as I had a scan showing 9mm womb lining and a few v small fibroids.
I paid for a private scan showing smaller fibroids and 4.2mm lining, and very much retired ovaries.
Can more be done to help women through this very daunting and scary time of life? I really feel for people who can’t go private.
thank you for highlighting and advocating for womens health .

@hushabybaby there urgently needs more training and education for ALL healthcare professionals. We have created a course - www.newsoneducation.co.uk There is so much resistance to learn and I have no idea why. SO many women are needlessly suffering and being prescribed the wrong medications when safe and effective hormones would help them so much more...

Experts' posts:
Monetsbridge · 03/06/2026 20:06

DrLouiseNewson · 03/06/2026 19:09

Estring will only help with localised symptoms and contains a type of estrogen. Often prasterone (vaginal DHEA) is more effective. There are many reasons for bleeding so would be good to get checked. There are also benefits from systemic hormones. Estring can be used longer than 2 years - all vaginal hormones can be used in the long term as they are low dose and safe

Thank you; yes it was localised urinary symptoms that I was prescribed it for, and I do prefer having something I can leave in - do any other hormones come in a similar sort of ring fit?

But the medication instructions clearly state the 2 years maximum use - I'm sure it's just that it hasn't been tested, and/or that it's just quoting the guidelines for systemic hrt, but because that's what the manufacturers recommend, my GP says it will only be for 2 years, which makes me a bit wary about whether I should continue now, or wait until things get worse, so that I don't get used to it and then have to stop.

Is there an actual reference or manufacturers guideline anywhere that says over two years is fine?

Darkspiderplant · 03/06/2026 20:07

Hi Louise, I have had a mirena coil for 2 years for the progesterone of my HRT. I was having fairly regular periods before I had it. I’ve not had a period in 18 months. How do I know if I have gone through the menopause?

DrLouiseNewson · 03/06/2026 20:10

Ownedbykitties · 02/06/2026 17:59

Hello Dr Newson
Can women in their 70s, who have never been on HRT (because GPs were refusing to prescribe after the medical paper that reported it was harmful to women was out) start on it now to prevent the many health conditions that female hormones are known to protect against?
Thank you.

@Ownedbykitties Yes older women can start hormone treatments - especially natural, body identical hormones - progesterone, estradiol and testosterone. There are millions of women who have missed out on hormone treatments resulting in both suffering and health risks from being denied hormones

Experts' posts:
DrLouiseNewson · 03/06/2026 20:11

MVQGR · 03/06/2026 09:41

After reading your latest book, I no longer feel safe keeping the Mirena coil in place since last December, due to the long-term risks of brain tumours. I am currently using 175 mcg Estradot patches and Testogel daily. What would be the safest way to have the coil removed, and what options are available since I believe I'm sensitive to Utrogestan, as I experience intrusive thoughts? Thank you.

@MVQGR I hope you enjoyed my new book! Often in the clinic we prescribe Cyclogest which is body identical progesterone that can be given rectally or vaginally with good results. There are always options

Experts' posts:
DrLouiseNewson · 03/06/2026 20:13

WinnieM78 · 03/06/2026 09:49

Hi there,
How can I get my doctor to prescribe me progesterone? I had a total hysterectomy including BSO 18 months ago and had the worst time after - crippling anxiety, unable to eat, sleep, function and eventually suicidal thoughts. I struggled to get any support after - refusals to up my dose of HRT which was 50 prior to the operation - advice to use mindfulness apps...went private and was prescribed progesterone (alongside a higher dose of estrogen) and it has transformed how I feel and my entire mental health. Unfortunately, my GP maintains that it is only a necessity if you have a uterus, despite me providing evidence of the improvements and various evidence I've hunted down to back up my request. What would you advise?

@WinnieM78 can you see another doctor? I hear this a lot and it does not make sense. I have no understanding of why so many doctors are resistant to prescribing a natural, body identical hormone when they prescribe synthetic hormones to women all the time...

Experts' posts:
Monetsbridge · 03/06/2026 20:13

what forms does the cyclogest come in? Is there a ring or pessary form or do you have to use it daily? Why don't GPs ever suggest anything like that - is it quite new?

DrLouiseNewson · 03/06/2026 20:16

TendeleStardust · 03/06/2026 12:54

I'm 48, my mother had ovarian cancer. GP reluctant to start HRT, gave me clonidine but I don't want to take it due to drowsiness - I'm fatigued already! Brain fog, anxiety, moddy/weepy, had hot flushes with pounding heart for a couple weeks but that's subsided. Periods are irregular. Thinking of starting Zoely becuse I hear its protective for cancer and I can switch to HRT later on. Is that OK? Currently not on contraceptive as husband had the snip. Also I'm taking Rheal ashwaganda supplement and asthma tablet montelukast - may they help/hinder the symptoms?

Edited

@TendeleStardust sorry to hear about your mother - I have no idea why your GP is reluctant to start HRT for you - there is no risk of cancer with body identical hormones - progesterone, estradiol and testosterone. You should see another doctor

Experts' posts:
DrLouiseNewson · 03/06/2026 20:17

ElzasMama · 03/06/2026 13:15

Dear Dr Louise,
I'm 44, been perimenopausal for about 4 years, and just started my HRT this year (fitted Mirena Coil in February and got a prescription for 2 pumps of daily Oestrogel today). Judging by my symptoms, I will need to add Testosterone too at some point. When would be best to do that? Is it better to find an optimal dose of Oestrogen first, or to start Testosterone sooner rather than later?
Many thanks!

@ElzasMama There is no need to wait for testosterone if you have low testosterone on a blood test and symptoms of low testosterone. It is a very beneficial hormone for symptoms and future health - we have known this for decades but it is ignored by far too many doctors

Experts' posts:
DrLouiseNewson · 03/06/2026 20:19

Monetsbridge · 03/06/2026 13:21

Some of the most recent research (2026) on HRT and dementia has specifically linked HRT started later or used for longer times with higher rates of dementia, in those with genetic susceptibility to dementia only. I think I would be in this category, so am hesitant to start, despite other potential benefits. Some of the research suggested the effects were not found in those women without a uterus who were on an oestrogen only regimen. Do you know anything further about this research, and whether the effects were not would be similarly reduced in women with a uterus who used a local progesterone like mirena instead of a systemic one?

@Monetsbridge the risk of dementia is only with the SYNTHETIC hormones not with body identical hormones - there is SO much confusion out there. I have written about this and the roles of hormones in our brains in my new book - https://bio.to/ThePowerofHormones?mc_cid=50db8125f1&mc_eid=9520600d61

The Power of Hormones

Go to The Power of Hormones.

https://bio.to/ThePowerofHormones?mc_cid=50db8125f1&mc_eid=9520600d61

Experts' posts:
DrLouiseNewson · 03/06/2026 20:21

menoworries · 03/06/2026 19:38

Hi, i'm 35 and I'm pretty sure I'm entering peri. Is there anything I can be doing to help, in particular with brain fog? Natural if possible...

@menoworries it is more natural for our bodies to have hormones - progesterone, estradiol and testosterone - then not have hormones. They are all biologically active and have important roles in our bodies. There are more risks of not taking hormones than taking hormones - What are the risks of not using hormone therapy? https://link.balance-app.com/content/CWfcxX8VMXWFl4FMKE4WXI

Balance

Balance - Menopause support, symptom tracking, and expert-led content.

https://link.balance-app.com/content/CWfcxX8VMXWFl4FMKE4WXI

Experts' posts: