LoveMyJob I’m glad that the pain management strategies you have in place are giving you a decent level of pain control - I have been on long term opioid therapy for 17 years (not 19, as I prev wrote - typo!), and my tolerance has actually only risen moderately. I didn’t get on well with fentanyl patches because my tolerance did build very quickly - I was ending up needing breakthrough doses very rapidly: I think I didn’t get on well with transdermal also because it didn’t give me scope to take less on good days. The fentanyl was the only one I had physical withdrawal from - absolutely nothing in the league of what OP is describing WRT heroin withdrawal, it wasn’t like the Trainspotting cold turkey scene. But I did feel utterly dreadful - achey, shivery, anxious, agitated, beyond restless, wanted to crawl out of my own skin: no diarrhoea or vomiting, but I did feel pretty bloody awful. My own fault entirely for not stepping down as slowly as I should have done.
Tramadol I needed to step down from VERY slowly - not because of the opioid withdrawal, but because of the serotonin and noradrenaline effect, the anxiety and agitation of coming off it too quickly was not pleasant.
But I tolerate the oxycodone MR and IR very well. You never get immune to the constipating side effects, but Movicol sorts that out. The only benefit to being off all the meds during my (sadly unsuccessful) pregnancies was the joy of daily bowel movements!
I used to collect my prescriptions from a central London high st chemist near my office, and when I’d go in during my lunch break, I would not infrequently be in the queue with people who were waiting for the CDs cupboard to be unlocked in order to get their methadone (which of course they had to drink there and then). Because I could take my meds with me, I was told by the pharmacist to put them straight in my handbag and to go immediately back to the office - as they were concerned that I could be mugged for what was a large quantity of opioids.
I’m thinking about kids soon and terrified, will have to see a Pain gynae doc to get their advice on what to do re medication and pregnancy, I’m not sure how I could function at all getting and staying pregnant without pain relief. Especially as mine is all urethra/bladder focused.
I consulted both my pain consultant and my gynaecologist about this before starting TTC - my gynae recommended I see a colleague of his who quite literally wrote the book on prescribing in pregnancy. He is one of only a small handful of consultant obstetric physicians in the country - whereas OBGYN deal with pregnancies and babies, obstetric physicians deal with the management of maternal medical disorders in pregnancy. He was absolutely terrific, and was basically the authority on management of both my pain and my epilepsy in pregnancy (which turned out to be academic, as I’m infertile and could never make it beyond the first trimester in my pregnancies). The general gist from him was nothing whatsoever in the first tri, some opioids would be reasonable in the second tri, and third tri stepping down in order to be weaned off by the time of delivery, to avoid the baby suffering withdrawal.
There's no meaningful research done on any kind of prescribing in pregnancy due to ethical issues, so it really is based on professional experience . I would strongly recommend seeing him privately if you can - his name is Dr David Williams, and he is the top guy in the UK, you won’t get better advice tbh.
The specialist women’s physio I see for pelvic issues wouldn’t touch me during the first tri either, but said to come back after 12 weeks (again, sadly academic in my case)
I’d recommend pre-TTC counselling and go to the right people. My OBGYN said he would make recommendations cautiously based on his experience, but he wanted to refer me to Dr Williams as he said he was the go-to guy for any such issues.
Sorry for thread-derail OP! And thank you for your really insightful input too Toothy
I’m hoping I have no cause to ever end up in prison, though tbh if that happens I do think that my pain management may be the least of my issues were that to be the case! But reassuring to know that cases are managed on an individual basis