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Immune/NK cells pred thread #31

983 replies

VenusStarr · 13/04/2023 09:05

Hi all, we've fill up the last thread, so starting a new one. Will start tagging but feel free to add anyone I miss!

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Gizmo1983 · 24/04/2024 10:09

Hey @VenusStarr if you need to increase them you go for it I totally know that feeling you are talking about and it is just terrible. I have this terrible habit of when it’s just me in the house crawling into bed and just sleeping I think it’s just to block everything out and I know it’s really not good for me I do need to get myself on some meds myself just I’ve tried a few times and my gp was so reluctant I just can’t be bothered to fight with them. I almost have the feeling now about the ivf that you describe, ivf ( to me ) was the safety net that i thought i would never need falling pregnant was never my issue it was keeping them but now i can’t even get pregnant. I keep thinking of what I could do with that money and I’ll be fine if it works and feel even worse if it doesn’t but I’m sure we all have thoughts along the same line it’s just really not fair is it? If these 3 don’t work then we’ve factored in having a go with donor eggs (looking at Spain) and then we’re done.
The pains have all settled thank goodness I was really scared last week that something had gone really wrong I’m testing out the trigger from the hcg injection as it’s test day Friday/Saturday as not sure when i ovulated but I have very little hope . I can totally get you being so hesitant about that last go and if you can bring yourself to do it you should go for it but you need to be mentally ready. I was having my Intralipids with a lovely lady who sadly had cancer as a teen this was before they froze eggs before chemo so she was donor eggs and they’d tried numerous times and were done then her hubby said do one more if you want and they did and it worked. Also a lady in my street had done ivf so many times and gave up and fell naturally at 43. I keep thinking of these stories to pull me through. My husband every month is this is the month I can feel it, you look different etc and he’s been doing this for a year he drives me mad with it but even he is relieved we are starting ivf, it hasn’t so much taken a toll on our marriage but the timing and pressure has us both worn down. I’m having counselling as well I’m thinking of training to be a counsellor in this field when my journey has ended either way I’d like to give something back. Any progress on the tattoo ❤️. Thinking of you

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VenusStarr · 24/04/2024 09:45

Hi everyone. Sorry for disappearing. Feeling quite disconnected at the moment. Not sure if I don't need to increase the antidepressants. I also think I'm coming down with something.

Thanks for checking in @Gizmo1983 how are you feeling? Have the pains subsided now? I hope things have settled ❤️
Just seen your message about the ivf. It is overwhelming, take it easy in yourself. I think I put so much pressure on myself.

@MotherOfShihTzus is it Doxycycline? I had that, was a 2 week course. I started on cd1.

Thank you @lozzmax how are you? Dr S is against pgta for us too. We can't make day 5 blasts now, so it's a moot point as I'll be doing a day 3 transfer, if we decide to go back to it. My therapist said last week that she thinks I do want to do the final round of ivf, but I've got anticipatory grief 😔

How did your scan go @Sunflower360 hope all is on track for your FET. How you feeling about it?

I hope everyone is ok ❤️❤️

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Gizmo1983 · 24/04/2024 09:38

@Sunflower360 just the recommended dose optibac are the ones I use. And then I take a cheap amazon one as an added extra lol.
@MotherOfShihTzus if it’s doxycycline I believe it’s 2 weeks worth xxx.
does anyone know how to start us a new page as we are on p40 I would do it myself but wouldn’t have a clue how to do it. Can’t believe yesterday we signed up to 3 ivf cycles feeling quite overwhelmed today xxx

MotherOfShihTzus · 24/04/2024 08:58

Does anyone have experience of taking antibiotics in case of infection? I've not done the testing, but have a course ready to go. What's the best approach to taking it? I was planning on the cycle before my next FET? How many days worth? I just want to eliminate anything that could possibly wrong in the uterine environment - desperate for the next one to work after 2 back to back early IVF losses

Sunflower360 · 23/04/2024 22:03

@Gizmo1983 Thanks, looks like Optibac has that in. How many did you take a day?

Gizmo1983 · 23/04/2024 20:45

These are the 2 that you want in your probiotics for womb/vaginal flora xxx

Immune/NK cells pred thread #31
fleur89 · 23/04/2024 16:53

I just took symprove 3 months prior to trying. Currently 20 weeks with Dr S and was on his complex protocol (discharged as of today)

lozzmax · 23/04/2024 16:29

@Sunflower360 thank you so much, I'll get those ☺️

Sunflower360 · 23/04/2024 15:14

@lozzmax I'm taking these to help with the building good bacteria. I'm not sure if needed as I've not had my levels tested, but the Dr was happy for me to try it this FET as it is low risk

www.boots.com/Optibac-For-Women-30-capsules-10274771?cm_mmc=bmm-buk-google-ppc--LIAs---_-PMax:+UK_Smart_Shopping_LIAs_Health&gad_source=1&gclid=CjwKCAjwuJ2xBhA3EiwAMVjkVA0nB4r9kXbWZwtjzdevCPWSS52HqUf3lYJAkBMiBGzYwfZ8pn8nNRoCnX4QAvD_BwE&gclsrc=aw.ds

lozzmax · 23/04/2024 14:35

What are the probiotics that you're all taking? Should I be adding those in as well?

Sunflower360 · 23/04/2024 14:34

Good luck to you too!

Sunflower360 · 23/04/2024 14:34

@Gizmo1983 thanks! Well I've had a few ECs already to embryo bank and have had 2 natural FETs back to back both BFNs...this is my 3rd FET now so thought I'd try probiotics this time too

Gizmo1983 · 23/04/2024 14:32

@Sunflower360 oooh good luck let us know how you get on as I think there seems to be a few of us going the ivf route. I’ve pretty much overdosed on probiotics for the last 2 years and never had an issue. I think you’ll be a lot safer with them than without them. Xxx

Sunflower360 · 23/04/2024 14:14

@Gizmo1983 thank you! Have started them today for (hopefully) having an FET this cycle

Gizmo1983 · 23/04/2024 14:07

Hi @lozzmax it messes with your head all this doesn’t it 🤪. We’ve literally signed up to ivf today to start in June. I’ve had 2 losses one a blighted ovum at 8 weeks defo chromosomal) the other 15 weeks no issues found and I’ll be 41 in July also have a blocked left tube.
we are doing pgtA testing unless we get one single blast and then we will put it in and pray.
I may be wrong but if dr S believes there are chromosomal issues then wouldn’t ivf with put testing help with that issue rather than keep having chemicals as no amount of any drug they can prescribe can fix chromosomal issues.
my last pregnancy I ovulated on day 21 and all went well until probably a placenta issue at 15 weeks, and I know a few who have ovulated late and had healthy pregnancies. I am absolutely no expert.
I need to inform Mr S clinic, he asked me to do 3 cycles before I went to ivf which I have and super ovulation just isn’t an option for us with living 6 hours away. Although I did do the equivalent this month as I had 2 follicles on my right and one on my left. So they have me the hcg injection which is the equivalent of super ovulation kind of. I’m in the 2ww for this one but with all the issues I’ve had it would be a miracle 🤦‍♀️🤦‍♀️🤦‍♀️.
im feeling much better thank you from
thursday every day the pains improved and im pretty much back to normal though im told i still look a bit peaky 🤦‍♀️🤦‍♀️🤦‍♀️. I have to go back to the nhs to have a scan in 10 days just to be safe.
@VenusStarr how are you doing
@Sunflower360 i have taken probiotics throughout ( including swallowing my vaginal probiotics for a week by mistake 🤪🤪🤪) I’ve been fine no issues

Sunflower360 · 23/04/2024 12:44

Hi

Has anyone used probiotics alongside Prednisolone in this thread? Optibac online states it can conflict with Prednisolone as that reduces your immune system and probiotics introduce bacteria ap can lead to infections. I've been on Prednisolone for 2 months now

lozzmax · 23/04/2024 12:08

@Gizmo1983 how are you feeling? Hope things are better for you.

I was wondering if anyone could give me a bit of advice. We saw an IVF doctor on Friday who suggested to us that I am making a higher number of chromosonally abnormal embryos than I should be for my age (3 of my 5 losses have been pre 5 weeks). He suggested that PGTA testing frozen embroys would be a good option for me, as well as karyotyping tests. I saw Dr. S yesterday and he was vehemently against IVF for us, and said it would be throwing money away. However both times I have had a chemical under his treatment plan, he did say he assumes they were chromosonal abnormalities, the latest potentially being because of late ovulation. He said IVF wouldn't help us, and that there's no evidence to support PGTA testing helping women who have recurrent miscarriage. Does anyone have any insight or experience of this?

We've decided to do a managed cycle next month (super ovulation) just so we prevent late ovulation again and so we have a bit more control, but feel like if we have another loss, we should try IVF, though I know Dr. S won't advise it.

@VenusStarr I hope you are feeling ok mentally. I am so sorry for everything you've been through, it must be really taking its toll x

Gizmo1983 · 19/04/2024 10:29

Hi @VenusStarr i realised this morning I hadn’t asked how you were and I feel so bad I feel like I was just moaning about myself so I’m really sorry and how are you doing? Xxx
@lozzmax thwnk you so much for your kind words
just out the scan there was nothing to really see that could explain anything. The only thing is they could see 2 corpus luteums so 2 eggs have ovulated and they think that may be what’s causing the pain. They said they would consider an ectopic pregnancy but I’ve had a hysteroscopy, a hyfosy and I hadn’t ovulated till Tuesday so can’t be that. The only thing they can’t totally rule out is a twisted ovary but they said I’d be in agony and she could touch my tummy without me being in agony so they don’t think it’s that only way to be 100% sure is a laparoscopy I have open access to the ward so if pain increases or gets worse I can go straight back and they want another scan in 10 days to see if anything has changed. To add insult to injury I will ovulate from my left ovary next month which is the one with the blocked tube 🤦‍♀️🤦‍♀️🤦‍♀️. So my best hopes is that whatever this pain is I’ve not done any damage and we start ivf in June which to be honest will be a relief after all this and if I have 2 healthy ( granted 40 year old) ovaries to do ivf with I guess I’ll take my lot xxx I shall go home and start my prednisone 🤪🤪🤪

lozzmax · 19/04/2024 08:57

@Gizmo1983 thinking of you today, let us know how you get on x

VenusStarr · 18/04/2024 20:49

I'm glad you'll be seen soon and that you can sleep in your own bed @Gizmo1983 ❤️ hopefully it's nothing serious and glad there's no infection. I'll be thinking if you tomorrow xx

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Gizmo1983 · 18/04/2024 20:35

@VenusStarr just got back home I have to go back 8.50 in the morning for a scan and we will take it from there. I’m sooooo relieved no infection present am nervous for the scan tomorrow. It just feels like my right ovary is not happy they said it could be a cyst or twisting but they won’t know till they do the scan xxx

VenusStarr · 18/04/2024 19:41

Glad they're looking after you @Gizmo1983 ❤️ do you think you'll need to stay overnight? Good plan with the pred. Let me know how you get on xx

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Gizmo1983 · 18/04/2024 19:08

@VenusStarr thank you so much ☺️ I was due to start pred today but I haven’t in case they needed to give me any drugs depending on the scan I’ll start it tomorrow. I’ve kept up with my hydroxy and other vitamins xxx yes thank you hubby met me up there after work I was tucked in a little corner on the ward I got admitted to so was happy. It will just be nice to know what’s going on my brain really needs a holiday xxx thank you for being there for me once again it honestly means so much 😊😊😊

VenusStarr · 18/04/2024 18:59

Oh @Gizmo1983 ❤️😞 maybe it's a cyst?
I really don't think you have damaged an ovary but I understand how your mind can worry.
I hope you're not waiting too long to be seen and hope you are reassured that all is OK and they can get to the bottom of it.
Have you started pred now?
Definitely better to be checked, you're in the best place. Is your partner with you? Hooe all is well xx

Hi @Sunflower360 👋 the only thing I know for thyroid antibodies (other than pred) is LDN but I don't know much about it, dose etc. I hope you're OK x

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