ABOUT FEMALE BRAIN STRUCTURE AND CONCUSSION
Tweet from Dr Emma Hilton
x.com/fondofbeetles/status/2046635369664319628?s=46
“If you grow male brain neurones and female brain neurones on a plate, then subject them to injury via stretching, the female neurones "break" earlier and the male neurones recover quicker, because they activate a stronger and more efficient inflammatory response.
Female brains are more fragile under injury conditions, and they don't recover as well.”
Plus an article from the Irish Times
https://www.irishtimes.com/health/your-family/2026/04/21/pink-concussion-how-womens-brain-injuries-differ-biologically-from-mens/
https://archive.is/R0wo8
in this article, US neurologist Dr Beth McQuiston states:
“When it comes to the biology of concussion, there are three main differences between men and women that we know of, she explains in a video call from her home in Chicago. “Women tend to have less muscular necks. So when an injury occurs, say whether it’s a car accident or if it’s on a pitch, there is less support here,” she says, putting hands up to either side of her neck.
Secondly, there is a difference in the microarchitecture of the brain. Women have more neurons crossing the corpus callosum – a structure in the middle of the brain that connects the right and left hemispheres – and they are thinner.
A third factor is the menstrual cycle. “Given the same woman at a different time, exact same injury, there can be a different outcome, depending on whether progesterone levels are high or low. It is worse if it is in the luteal phase [ie after ovulation, approximately days 15-28 of a 28-day cycle], when the progesterone levels are high and then all of a sudden they drop abruptly.” This is due to the effect of the trauma on the pituitary gland, right in the centre of the head.
“That is very intriguing,” says McQuiston. “We’re looking at studies right now, [asking] can someone be on a certain type of oral contraception, or can they take a certain kind of medication, to attenuate that drop if they had a concussion?”
Research indicates women have more post-concussive symptoms and usually take longer to recover. “