I had a LOT of problems with an old landlord, and as a result I have spent far too much time studying EPCs and I can promise you, they are utter bollocks.
The assessors get paid as little as £35, sometimes that involves several hours round trip plus doing the report.
Something like 65-70% of them are inaccurate.
They don't regionally vary them in the slightest. You could be on an island big enough for one house and get battered by wind and it would be rated the same as an inland location that is sheltered.
They don't test heating systems to see if they work, which is useless for renters. They don't look closely at boilers either, which is important for good heating.
40% of the time they get the house size wrong. I have seen 2500 sq ft houses listed as 1500 on EPCs (in sq meters).
If they have no way of knowing if you have floor, wall or loft insulation, they guess.
They frequently lack changes to houses, improvements, extensions.
Our last house was an E40 - the lowest possible score they can have whilst being legal to rent. We got through the 26,500 kw annual estimate in 4 months. That house was so cold that we completely abandoned the ground floor after six months.
Our current EPC is a C. It's a 10 year old self build, our landlady built it.
So, whilst it is in theory very energy efficient, because there is no accounting for location or measuring weather, it couldn't tell us that we will get absolutely hammered by wind on one side of the house for 7-8 months of the year and get through four tonnes of wood on top of the EPC's general annual kWh estimate, which, this time, is more reasonable.
I have also lived in a B rated flat but because the underfloor heating was faulty, it used up twice the annual kWh in that home, too.
To say use it as a guideline only would be honouring the system with far more accuracy than it deserves.
The only really way to guage energy use is to talk to the owners about their consumption, their energy use habits and what the house is made of and hope they are being truthful.