4 PEANUTS eaten by previously anaphylactic child on STOP study - there will be dancing in the streets!

[BlueBumedFly]

Hello All

Back at Addenbrookes today as DD was struggling to eat the peanut butter dose. She is totally abhorrent to the taste and it was making her heave, it is so very sticky and cloying. Bleugh.

So, change of tactic and she went up today and ate 4, yes, wait for it, 4 PEANUTS!!

She still hates the taste, I am sure the body knows you know!

Anyway, all is well, slight stomach ache but OK other than that. Next step is the 11 Nov when she will have 10 peanuts!! DH and I will have run out of cooking sherry by then with all the nerves!

He is very well indeed BBM. He is nearly as tall as me, cheeky, amusing and a friend to everyone. I'm still boggled occasionally when I think back to the lifeless little scrap he was a 4 months of age. Amazing really.

Keep pushing on.

BBF hope you don't mind me writing some more about the safety of this - partly for Kerry but more that it must have shaken you and it may help.

I've only found one report of a child death in a peanut desensitisation study. And I also found this " Due to a pharmaceutical error, a placebo subject received a peanut injection. Results from that study, however, showed that desensitization was possible." Perhaps they weren't fully prepared for that reaction/ didn't respond as fast because the child wasn't supposed to be getting peanut.

Previous studies have used injections. The Addenbrooke's study is giving peanut by mouth. There are studies in mice that have shown this works. Thre are suggestions that its important for children to be exposed to allergens by mouth rather than through the skin so possibly this is a better method. I imagine this is one of the reasons Adenbrookes are prepared to try.

There are studies underway in America at several centres - Mount Sinai School of Medicine in New York; John Hopkins University School of Medicine in Baltimore; Duke University School of Medicine in Durham, NC; and the University of Arkansas Children ?s Hospital Research Institute in Little Rock, AR. These involve ages 12-40 years for peanut allergy and 6-18 years for egg allergy.

Hello - what interesting news....

I spoke to Mr Clarke when he started the study because they were interested in dd as she'd had confirmed allergies (i.e. tested in her blood), some of them severe, but then outgrown them.

So I think this study had other angles too (he mentioned to me they were interested in trying to find out why some children outgrow allergies and why others don't).

Thing is Kerry, somebody has to volunteer for these things and all credit to those who do. Unfortunately, with both dh and me working full time, we just couldn't get up to Cambridge but volunteered to have dd blood tested down here (would have been of interest to us too as we weren't sure whether her allergies would still show up and also, I have a suspicion that she has developed a sea food allergy and was quite keen for her to see the paediatrician again) but it just never worked out. If a treatment or a progression in treatment comes of this, then everyone will benefit!

And I also find it surprising when people say the allergies aren't a pita. I found them all a total pita to deal with, especially when having to make sure that everyone (school, nursery, people they visited) had actually understood the severity of the situation! In fact, I ended up having to give up work for a couple of years because dd was so consistently unwell because her nursery kept feeding her foods she was allergic to .

Still reading Fi?!

bluebumedfly, do you have a link for the study?

Hi BBM, I'm so happy to hear the news. Will keep paying attention to all your threads.

I just wanted to say thank you, thank you for having the courage and initiative to help change your DD's life. People like you and your family are the ones who by trying to help your child are actually giving a chance to so many of us who have to deal with this terrible allergy.

So a huge grateful hug from us all. Science and medicine wouldn't advance without the help and courage of people preparing to take the steps to make changes happen

Have I missed a thread from BBM for the 11th Nov. I had this one still on watch waiting for news?
Anyone know?

Tis OK, I found it after opening my eyes and looking, lol