The other point of note here is the vaccine availability.
Yes, the U.K. does have large stockpiles of the old smallpox vaccine which was routinely given until the early 70s in the U.K.
It has some pretty significant side effects by today’s standards and can’t be taken by a lot of people e.g. those with eczema, pregnant.
www.drugs.com/acam2000.html
we were prepared to take these earlier, live versions of vaccine to eradicate the much more serious disease of smallpox
www.gavi.org/vaccineswork/how-smallpox-vaccine-stockpile-could-stop-monkeypox-its-tracks
and in the event of a bioterrorist incident with smallpox or a version of monkeypox which had been deliberately genetically modified to cause more severe disease.
news.bbc.co.uk/1/hi/health/1926780.stm
But I don’t think it will be given for just for plain old monkeypox.
The US have ~30 million doses of a newer, safer non replicating vaccine in their strategic national stockpile and it has been licensed for monkeypox.
It is called JYNNEOS from a Danish company called Bavarian Nordic.
www.cdc.gov/smallpox/bioterrorism-response-planning/public-health/vaccination-strategies.html
www.precisionvaccinations.com/bavarian-nordic-mva-bn-non-replicating-smallpox-vaccine-distributed-liquid-frozen-formulation?amp
The U.K. has just bought 20,000 doses of a JYNNEOS. It’s a two-dose regimen so enough for 10,000 people. I don’t know when we are taking delivery of that.
Apparently we have 5000 doses of it already and we are using it right now.
assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1077678/Recommendations-for-use-of-pre-and-post-exposure-vaccination-during-a-monkeypox-incident.pdf
It will be interesting to see in the coming weeks how the U.K. government plans to scale up its vaccination capability and plan for roll-out e.g. close contacts of cases> health care workers> all men who have sex with men(?)
Will 20,000 doses be enough?
After the recent outbreak of monkeypox this month, US almost immediately exercised their (3rd?) option with the manufacturer for a further 13 million doses of JYNNEOS but I don’t think they will be ready until 2023/24.