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Feminism: Sex and gender discussions

Sex differences in viral severity

39 replies

Bowlofbabelfish · 24/12/2018 20:24

An interesting one - apologies I think it’s probably pay walled but the gist is this. Many viruses hit women less hard than men and it may be because women can pass them down to their infants. A virus will evolve be be less severe usually if the host can pass a lot of it on.

www.newscientist.com/article/2115987-viruses-may-have-evolved-to-hit-men-hard-but-go-easy-on-women/

Two interesting quotes:

For this to be the case, though, the virus would have to be able to detect whether it’s inside a man or a woman. We don’t yet know how it would do this, but it’s not impossible, says Jansen. “There are all sorts of hormonal and other pathways that are slightly different between men and women,” he says.

The study emphasises the need to conduct clinical trials in both sexes, rather than predominantly in men as is often the case, says David Duneau, an evolutionary biologist at the University of Toulouse, France. “The parasites themselves are behaving differently in males and females, so we need to know what they do in both sexes,” he says.

Just a small reminder that Real Scientists doing Real Science are fully aware that sex and sex difference is indeed a thing ;)

And a very Merry Christmas to you all Xmas Wink

OP posts:
Mummymumm · 25/12/2018 08:17

Just sounds like male scientists are making shit up to get away with being idiots when they're ill. I read an article that said giving blow jobs help ease morning sickness. 🙄

Yeahnahyeah · 25/12/2018 08:01

Interesting
Thank you

Igneococcus · 25/12/2018 07:46

It feels like the wrong way round to me.There just isn't enough genetic information for viruses to make that distinction, other pathogens maybe but not viruses.
Humans having evolved to respond differently to viruses, that I could get on board with more easily.

WrathofRancidKlopp · 24/12/2018 23:51

Matriarch, irene and Contessa
Yes
Man flu must be a thing.

I'm fine with that, if science backs it up.

Unlike the other shit.

WrathofRancidKlopp · 24/12/2018 23:45

Correction

No signalling in the male body-
This would allow the virus to replicate there and cause illness to its male human host.

TheMatriarch · 24/12/2018 23:41

I'd happily let manflu go if they'll just give up on the sex is a spectrum/gender is science bollocks.

ChristmassyContessaConSparkles · 24/12/2018 23:39

That was my first thought too Irene!

I'm torn between never telling them and shouting from the rooftops that sex difference is real Grin

IrenetheQuaint · 24/12/2018 23:35

Hang on - are we saying that manflu is real??

WrathofRancidKlopp · 24/12/2018 23:34

Interesting stuff Bowl.

It appears the virus may have the ability to know it is in a female body, thereby allowing the female human host to reproduce successfully.
It might even alter the behaviour of its host via neural pathways.

No signalling in the male body would allow the virus to replicate there and cause illness to its male human host.

Whilst the virus knows human females are still reproducing.

Clever

nauticant · 24/12/2018 23:21

It turns out that distinguishing between the sexes is a common ability whether it's adult humans, infant humans, dogs, cats, whatever, and all the way down to viruses.

But still beyond the woke and many blokes with beards. What would Charles Darwin have made of it all?

AspieAndProud · 24/12/2018 21:44

Bats, not bars. I still think bars are cute.

AspieAndProud · 24/12/2018 21:43

I read David Quammen’s Spillover earlier this year. Fascinating as well as scary. And I used to think bars were cute.

So things like Ebola and HIV and SARS - if they hang around in humans for a long time they will get less lethal.

HIV takes a long time to kill its host. It’s not as easy to catch as many other viruses either. But so long as R0 > 1 any disease will persist in a population.

Bowlofbabelfish · 24/12/2018 21:23

Yeah absolutely, long term. Stuff that’s really really hideous tends to be stuff that’s new, that’s just spilled over into humans.

So warts - probably had those viruses for millennia.
Ebola? Very recent zoonotic (i.e from other animals) spillover. Ditto hendra, SARS etc. A virus is at its greatest lethality when it’s new. As it spends more time in a new host some immunity develops AND there is a selection pressure to be less lethal.

So things like Ebola and HIV and SARS - if they hang around in humans for a long time they will get less lethal.

Stuff like flu has been around a while BUT it also hangs out in other animals like pigs and fowl. So you get really nasty outbreaks when a new set of surface proteins have been shuffled in from other animals.

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AspieAndProud · 24/12/2018 20:41

To be honest, I’m surprised that any viruses can kill. It doesn’t seem like the optimum strategy for spreading.

Far better to be non-fatal, if annoying, like herpes.

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